New scoring system aims to better predict ulcerative colitis outcomes
NCT ID NCT07608198
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested a new scoring system called CAT-DESIRE to evaluate ulcerative colitis severity using colonoscopy images. Researchers reviewed images from 235 patients to see if the new score is reliable and can predict long-term outcomes. The goal is to provide a simple, accurate tool for doctors to assess disease burden and guide treatment.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this could give doctors a simpler, more accurate tool to measure disease burden and guide treatment decisions for ulcerative colitis.
- What could go wrong
- This is an observational study analyzing existing images and data, not testing a new treatment. The scoring system may not prove better than current methods in practice.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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235 people
The number who actually took part.
- Started
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Feb 2024
- Finished
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May 2026
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
A total of 235 UC patients were recruited from 9 specialized IBD diagnosis and therapy centers across China, with all patients undergoing paired endoscopic evaluations. Nine specialized IBD diagnosis and therapy centers are the Air Force Military Medical University First Affiliated Hospital, the Beijing Peking Union Medical College Hospital, the Xi'an Jiaotong University Affiliated Second Hospital, the Shanghai Ruijin Hospital, the Xinjiang Urumqi Affiliated First Hospital, the Sichuan Huaxi Hospital, the Wuhan Xiehe Hospital, the Shanghai Jiao Tong Renji Hospital, and the Seventh Medical Center of PLA General Hospital.
- Ages
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18 to 75 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * 1\. Adult patients (aged 18 - 75 years); * 2\. Diagnosed with ulcerative colitis for at least 3 months; * 3\. Have had endoscopic examination results for at least 2 times, with clear endoscopic images (including endoscopic pictures of the terminal ileum, cecum, ascending colon, transverse colon, descending colon, sigmoid colon, and rectum at least one picture for each of these 7 areas); * 4\. Complete clinical data. Exclusion Criteria: * 1\. Crohn's disease, intestinal Behcet's disease, intestinal tuberculosis, toxic megacolon and unclassified inflammatory bowel disease. * 2\. The length of the colon lesion could not be evaluated.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Peking Union Medical College Hospital
Beijing, Beijing Municipality, 100730, China
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Renji Hospital
Shanghai, Shanghai Municipality, 200127, China
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Ruijin Hospital
Shanghai, Shanghai Municipality, 200025, China
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The First Affiliated Hospital of Xinjiang Medical University
Ürümqi, Xinjiang, 830000, China
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The Second Affiliated Hospital of Xi'an Jiaotong University
Xi'an, Shaanxi, 710004, China
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The Seventh Medical Center of PLA General Hospital
Beijing, Beijing Municipality, 100700, China
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West China Hospital
Chengdu, Sichuan, 610041, China
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Wuhan Union Hospital of China
Wuhan, Hubei, 430022, China
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Xijing Hospital of Digestive Disease
Xi'an, Shaanxi, 710032, China
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Ulcerative colitis drugs put under the microscope for hidden clot risk
- Triple-Pronged attack on gut inflammation put to the test
- Can a cheap Anti-Inflammatory drug calm ulcerative colitis?
- Two biologics go head to head in ulcerative colitis
- New drug ATTO-1091 put to the test for safety in ulcerative colitis
- Antiparasitic drug tested as new weapon against ulcerative colitis