TYPE2DIABETES

This study tests whether a 6-month program combining exercise training, problem-solving skills, and support from community health workers can improve fitness and health in 210 adults with type 2 diabetes, obesity, and early signs of heart trouble. Participants have low income and…

This study compares two common diabetes medications (SGLT2 inhibitors and GLP-1 receptor agonists) to see which is better at preventing heart attacks, strokes, kidney failure, and death in people with type 2 diabetes who already have or are at high risk for heart disease. About 6…

This study tests whether plant-based nutrition classes can improve health and reduce healthcare costs for 700 Blue Cross Blue Shield subscribers with type 2 diabetes. Participants follow a plant-based diet for 16 weeks and attend weekly online classes. The study measures changes …

This study tests whether a supplement called NMN can improve kidney health in people with type 2 diabetes and diabetic kidney disease. About 156 adults will take either NMN or a placebo twice daily for 6 months. The main goal is to see if NMN reduces a key marker of kidney damage…

This study helps older adults with type 2 diabetes move away from sulfonylureas—older pills that can cause dangerous low blood sugar, falls, and heart problems—and switch to newer, safer medications. About 220 participants will be given simple questions to ask their doctor, while…

This study tests if Dialectical Behavioral Therapy (DBT), which teaches mindfulness and coping skills, can help teens aged 14-17 with obesity and mild depression improve their quality of life and manage weight to prevent type 2 diabetes. Participants are randomly assigned to life…

This study looks at whether a 6-week program of non-weight bearing exercise can help diabetic foot ulcers heal faster than standard wound care alone. About 40 adults with type 2 diabetes and a foot ulcer will be randomly assigned to exercise plus standard care or just standard ca…

This study tests whether taking vitamin B1 (thiamine) capsules can improve brain function in adults with type 2 diabetes. Many people with diabetes are low in thiamine, which may affect the blood-brain barrier and thinking skills. Researchers will use brain scans, memory tests, a…

This study tests whether a 12-week home-based strength training program, guided by video calls, is practical for adults aged 55-80 with type 2 diabetes and mild cognitive impairment. Researchers will track how many people finish the program and how often they exercise. The goal i…

This study tests whether screening for diabetes right after giving birth (before leaving the hospital) is more effective than the usual 4-12 week wait for new mothers who had gestational diabetes. It also surveys participants about their views on heart health programs and barrier…

This early-phase study looks at how SGLT2 inhibitors raise ketone levels and affect heart and muscle energy in people with type 2 diabetes and heart failure. Researchers will measure changes in heart energy molecules and walking ability. The goal is to understand the drug's effec…

This study follows 35 people with severe obesity who are having mini-gastric bypass surgery as part of their routine care. Researchers want to see how the surgery helps improve related health issues like type 2 diabetes, sleep apnea, high blood pressure, and fatty liver disease. …

This study looks at how diabetes changes the way heart cells use energy, which may lead to heart failure. Researchers will examine heart tissue and use imaging tests in 500 adults with heart failure, with or without type 2 diabetes. The goal is to better understand the disease an…

This study looks at whether giving doctors a special geriatric assessment for their elderly patients with type 2 diabetes leads to better treatment decisions. About 220 people aged 60 and older will be randomly assigned to usual care or to have their doctor receive the assessment…