TYPE 1 DIABETES (T1D)

This study tests whether a community health worker acting as a personal coach can help Black children and teens better use their automated insulin delivery systems. Sixteen participants with higher-than-target blood sugar levels will receive monthly coaching for six months, follo…

This study is testing whether a device called the iLet Bionic Pancreas can be successfully used by regular primary care doctors to help adults with type 1 or type 2 diabetes. Researchers want to see if using this automated insulin delivery system for 13 weeks leads to better bloo…

This study is testing if adding a once-weekly medication called tirzepatide to automated insulin pump therapy helps adults with type 1 diabetes manage their blood sugar better. Researchers will compare the new combination to standard insulin pump therapy alone in 42 participants …

This study aims to find a better way to monitor the health of transplanted insulin-producing cells in people with type 1 diabetes. Researchers will use continuous glucose monitors to see if a specific measurement, called 'Time in Tight Range,' can signal early problems with the t…

This study is testing if using ultrasound scans to find fatty lumps at insulin injection sites can help people with diabetes manage their blood sugar better. Researchers will train 50 participants with unstable glucose levels to avoid these lumps after an ultrasound scan and prov…

This is a very early safety study testing a one-time, personalized cell therapy called GNTI-122 in adults recently diagnosed with type 1 diabetes. The therapy is made from a patient's own blood cells and aims to help the body better control blood sugar. Researchers will monitor 1…

This study aims to collect real-world safety data on the Twiist automated insulin delivery system, which is designed to help manage type 1 diabetes. It will follow 1,875 adults and children in the U.S. who are already using the Twiist system for 12 months. The main goal is to tra…

This study is testing if a very low-calorie, ketogenic diet can help people with type 1 diabetes who are also obese lose weight safely. Fourteen adults will follow the strict diet for four weeks while using an automated insulin delivery system to closely manage their blood sugar.…

This study is testing if an automated insulin delivery system (a wearable pump that adjusts insulin on its own) works better than the current standard of care (an insulin drip into a vein) for managing blood sugar during labor and delivery in pregnant people with type 1 diabetes.…

This study is testing whether a new oral drug, CIR-0602K, can help adults with type 1 diabetes who use automated insulin pumps. Researchers want to see if the drug helps people spend more time in a healthy blood sugar range and reduces the total amount of insulin they need each d…

This is the first human study testing a new treatment called OPF-310, which involves transplanting specially encapsulated insulin-producing cells from pigs into people with unstable type 1 diabetes. The goal is to see if these transplanted cells can safely help control blood suga…

This study aims to identify people at high risk of developing Type 1 Diabetes before symptoms appear. Researchers will test blood samples from 30,000 children and adults across Europe who have a family member or close friend with Type 1 Diabetes. By looking for specific markers c…

This study is testing whether regular online meetings with other people who have type 1 diabetes can help reduce feelings of isolation and distress. It will connect 300 adults across Canada into small virtual support groups based on shared life experiences. The goal is to see if …

This study is testing a new phone app designed to help middle-aged adults with type 1 diabetes exercise more often and with more confidence. The app uses data from the person's continuous glucose monitor, along with their exercise, sleep, and mood, to provide personalized encoura…

This study is testing whether a mindfulness app called Calm Health can help young adults with type 1 diabetes. Participants will use the app to receive mindfulness guidance and see how their practice relates to their blood sugar, stress, and sleep. The goal is to see if the app i…

This study aims to understand how predictable blood sugar changes are during and after exercise. Researchers are comparing 12 healthy adults with 12 adults living with Type 1 Diabetes. Participants will cycle or rest after a standard meal while their glucose is closely monitored …

This study aims to find out if sexual activity increases the risk of dangerously low blood sugar (hypoglycemia) in adults with type 1 or type 2 diabetes who use insulin. Researchers will remotely monitor 100 participants for 3 months using their continuous glucose monitors. Parti…

This study aims to understand how obstructive sleep apnea (a condition where breathing stops and starts during sleep) affects blood sugar levels in adults with Type 1 diabetes. Researchers will observe 40 adults who have both conditions, using continuous glucose monitors to track…

This study aims to understand how exercising in hot weather affects blood sugar levels in people with type 1 diabetes. Researchers will compare blood sugar changes during and after exercise in normal (20°C) versus hot (40°C) conditions. The findings could help people with diabete…