TRIPLE-NEGATIVE BREAST CARCINOMA

This study is testing whether some breast cancer patients who respond exceptionally well to initial drug therapy can safely avoid surgery or radiation. It aims to see if careful monitoring with biopsies and scans can be enough for these patients, potentially reducing the side eff…

This study is testing a new, personalized vaccine designed to teach the body's immune system to recognize and attack a patient's specific cancer. It is being given alongside an existing immunotherapy drug (pembrolizumab) to adults with advanced solid tumors that have spread. The …

This study is testing if reducing calorie intake by 25% while receiving a highly focused, intense form of radiation before surgery helps shrink breast tumors more than radiation alone. It will involve 80 women with early-stage breast cancer. The goal is to see if this combined ap…

This study is testing whether giving a shorter, more intense course of radiation therapy *before* breast cancer surgery is as safe and effective as giving it *after* surgery. It aims to see if the pre-surgery timing can reduce side effects and treatment time for 120 patients with…

This study is testing if adding a hormone-blocking drug called darolutamide to standard chemotherapy and immunotherapy before surgery works better for a specific type of early-stage, triple-negative breast cancer. About 51 patients with this cancer type will be randomly assigned …

This study is testing whether a 10-week stress reduction program is practical and helpful for patients with triple-negative breast cancer. The program teaches relaxation, coping skills, and problem-solving, and also connects patients with social services for needs like transporta…

This study is testing whether following a specific healthy eating plan called the MIND diet can help reduce thinking and memory problems (often called 'chemobrain'), fatigue, and other symptoms in women undergoing chemotherapy for triple-negative breast cancer. Researchers will c…

This study is testing whether a multilingual AI chatbot named PERLA can help more cancer patients get important genetic testing. It compares patients who learn about testing from the chatbot to those who learn from a human genetics counselor. The goal is to see if this technology…

This study is collecting tissue and blood samples from cancer patients over time to create a research resource called a biobank. Researchers will analyze these samples to understand how cancer changes during treatment and why some treatments stop working. The goal is to help scie…