TOBACCO USE
Clinical trials for TOBACCO USE explained in plain language.
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E-Cigarettes tested as harm reduction for older smokers in opioid treatment
Disease control OngoingThis study looks at whether giving e-cigarettes to adults aged 50 and older who are in treatment for opioid use disorder can help them cut down on smoking. Participants are not trying to quit smoking at the start. The study will see if switching to e-cigarettes is a practical and…
Matched conditions: TOBACCO USE
Phase: NA • Sponsor: University of Maryland, Baltimore • Aim: Disease control
Last updated May 26, 2026 05:50 UTC
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Prison smoking study: can talk therapy beat the habit?
Disease control ENROLLING_BY_INVITATIONThis study tests if a short group therapy program (cognitive behavioral therapy, or CBT) can help men in prison quit smoking. Researchers will compare CBT to a health education class and a waitlist group. The goal is to see which approach works best and what factors predict succe…
Matched conditions: TOBACCO USE
Phase: NA • Sponsor: Centre Hospitalier St Anne • Aim: Disease control
Last updated May 26, 2026 05:47 UTC
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New study tests if automatically enrolling smokers in quit programs boosts success
Disease control OngoingThis study tested two methods to help smokers quit: an opt-out approach where everyone is automatically referred to Quitline or text messaging unless they say no, and an opt-in approach where people must actively sign up. Over 1,300 veterans from two VA clinics took part. The goa…
Matched conditions: TOBACCO USE
Phase: NA • Sponsor: VA Office of Research and Development • Aim: Disease control
Last updated May 18, 2026 12:00 UTC
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New outreach program aims to help BIPOC smokers kick the habit for good
Disease control OngoingThis study tests a proactive outreach program to help BIPOC adults who smoke quit tobacco. Researchers will use electronic health records to identify smokers and offer culturally tailored support, including counseling and medication. The goal is to reduce smoking rates and relate…
Matched conditions: TOBACCO USE
Phase: NA • Sponsor: University of Minnesota • Aim: Disease control
Last updated May 14, 2026 12:02 UTC
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One-two punch: quit smoking and boost mood after a heart attack
Disease control OngoingThis study tests a single program that helps people who recently had a heart attack quit smoking and manage depressed mood. About 233 participants will receive counseling that combines proven smoking-cessation techniques with mood management. The goal is to see if this combined a…
Matched conditions: TOBACCO USE
Phase: NA • Sponsor: Hennepin Healthcare Research Institute • Aim: Disease control
Last updated May 07, 2026 18:43 UTC
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Robot 'Anti-Smoking Kebbi' leads escape room to keep kids off tobacco
Prevention ENROLLING_BY_INVITATIONThis study tests whether a robot-assisted escape room game can teach 200 fifth- and sixth-graders about the harms of tobacco and e-cigarettes. One group plays the escape room with a robot guide, while the other gets standard classroom lessons. Researchers will check if the game i…
Matched conditions: TOBACCO USE
Phase: NA • Sponsor: National Taiwan Normal University • Aim: Prevention
Last updated May 26, 2026 05:59 UTC
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New program aims to steer native teens away from drugs and risky sex
Prevention OngoingThis study tests a program called Journey of Transformation for Native youth in tenth grade at an off-reservation boarding school. The goal is to see if it can delay or reduce tobacco, alcohol, and other drug use, and improve sexual health. About 182 participants will be followed…
Matched conditions: TOBACCO USE
Phase: NA • Sponsor: University of Washington • Aim: Prevention
Last updated May 19, 2026 11:48 UTC
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New program helps veterans with lung nodules kick the habit
Symptom relief OngoingThis study tests a program called TeaM OUT that helps Veterans who smoke and have a lung nodule quit smoking. Participants receive a letter about their nodule and the importance of quitting, plus proactive calls offering resources like counseling and medication. The goal is to se…
Matched conditions: TOBACCO USE
Phase: NA • Sponsor: VA Office of Research and Development • Aim: Symptom relief
Last updated May 22, 2026 13:51 UTC
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Nudge study aims to boost smoking cessation in HIV patients
Knowledge-focused ENROLLING_BY_INVITATIONThis study looks at whether sending simple reminders (nudges) to doctors, patients, or both can increase the number of people with HIV who get help to quit smoking. About 500 patients and their doctors will take part. The goal is to see which approach works best to connect patien…
Matched conditions: TOBACCO USE
Phase: NA • Sponsor: Abramson Cancer Center at Penn Medicine • Aim: Knowledge-focused
Last updated May 26, 2026 05:56 UTC
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Ottawa study aims to help homeless youth quit tobacco and other drugs
Knowledge-focused ENROLLING_BY_INVITATIONThis study looks at why homeless youth in Ottawa use tobacco, cannabis, and other substances together. Researchers will follow 520 at-risk youth aged 16 and older to understand their substance use patterns. Participants will receive a 6-month program with peer support and a menta…
Matched conditions: TOBACCO USE
Sponsor: Ottawa Hospital Research Institute • Aim: Knowledge-focused
Last updated May 22, 2026 13:53 UTC
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Smoking and vaping: do they slow down healing?
Knowledge-focused OngoingThis study looks at how different tobacco products—like cigarettes, e-cigarettes, and smokeless tobacco—affect the way skin wounds heal. Researchers will measure skin temperature, blood flow, and signs of inflammation in 60 adults, including a group of non-smokers for comparison.…
Matched conditions: TOBACCO USE
Sponsor: University of Minnesota • Aim: Knowledge-focused
Last updated May 22, 2026 13:52 UTC
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Can free Quit-Smoking help reach those in need? new study tests it
Knowledge-focused ENROLLING_BY_INVITATIONThis study looks at how Salvation Army staff can help people who smoke learn about and use free services to quit. About 233 adults who use Salvation Army services will take part. Researchers will track how many people are referred to the Wisconsin Tobacco Quit Line and how many a…
Matched conditions: TOBACCO USE
Phase: NA • Sponsor: University of Wisconsin, Madison • Aim: Knowledge-focused
Last updated May 19, 2026 11:47 UTC