TOBACCO DEPENDENCE

This study tests whether giving e-cigarettes to smokers with mental illness—who have tried to quit before but aren't ready now—helps them switch away from regular cigarettes. Half of the 250 participants will also get behavioral support via telehealth. The goal is to reduce tobac…

This study tests whether cannabidiol (CBD) can reduce cigarette smoking in people with tobacco use disorder. Researchers will give 120 participants either CBD or a placebo twice daily for 56 days, measuring nicotine levels and smoking abstinence. The goal is to find a new way to …

This study tests whether nicotine replacement therapy (patches, gum, or lozenges) combined with wellness coaching phone calls can help people experiencing homelessness quit smoking. Researchers will enroll 150 adults in San Francisco and Los Angeles who smoke at least 5 cigarette…

This study tests a new program to help people quit smoking by teaching them how to handle withdrawal symptoms and negative feelings. Researchers will enroll 400 adult smokers who want to quit. The goal is to see if this training helps more people stay smoke-free compared to stand…

This study tests a computer program where an avatar guides people through quitting smoking, plus a community health worker helps them get a lung cancer scan. About 30 adults aged 50+ who smoke will try it and be followed for 6 months. The goal is to see if the approach is practic…

This study looks at whether nicotine pouches can help people who smoke at least 5 cigarettes a day reduce their smoking by 75% or more over 16 weeks. About 375 adults will try different strengths and flavors of nicotine pouches while researchers measure their exposure to harmful …

This study tests whether yoga can lower tobacco cravings in men aged 18-65 who want to quit. 96 participants will either do low-impact yoga or receive standard quitting advice. Researchers will measure cravings and relapse over three months to see if yoga is a helpful addition.

This study tests whether a non-invasive brain stimulation technique called tDCS can reduce tobacco cravings and help people smoke less. About 100 adult smokers will receive either real or fake tDCS sessions alongside counseling. The goal is to see if this gentle, low-side-effect …

This study tests whether semaglutide, a drug used for diabetes, can help people with type 2 diabetes quit smoking. About 100 adults in Ontario who smoke at least 5 cigarettes daily will receive the drug alongside nicotine replacement therapy. The main goal is to see if a larger s…

This study tests whether a daily oral dose of cannabidiol (CBD) can help people stop smoking tobacco. Fifty adults who smoke more than 10 cigarettes a day and want to quit will take CBD during several practice quit attempts. The goal is to see if CBD increases short-term abstinen…