TOBACCO DEPENDENCE

This study tests a new program to help people quit smoking by teaching them how to handle withdrawal symptoms and negative feelings. Researchers will enroll 400 adult smokers who want to quit. The goal is to see if this training helps more people stay smoke-free compared to stand…

This study tests whether semaglutide, a drug used for diabetes, can help people with type 2 diabetes quit smoking when used alongside nicotine replacement therapy. About 100 adults in Ontario who smoke at least 5 cigarettes daily and have stable diabetes will participate. The mai…

This study tests a computer program where an avatar guides people through quitting smoking, plus a community health worker helps them get a lung cancer scan. About 30 adults aged 50+ who smoke will try it and be followed for 6 months. The goal is to see if the approach is practic…

This study tests whether coaching sessions and nicotine replacement therapy (like patches) can help people experiencing homelessness quit smoking. About 150 adults in San Francisco and Los Angeles who smoke at least 5 cigarettes a day will take part. The goal is to see if this su…

This study tests whether giving e-cigarettes to smokers with mental illness who can't or won't quit helps them switch away from regular cigarettes. Half the participants also get behavioral support via telehealth. The goal is to reduce harm by lowering tobacco use and exposure to…

This study looks at whether nicotine pouches can help people who smoke at least 5 cigarettes a day reduce their smoking by 75% or more over 16 weeks. About 375 adults will try different strengths and flavors of nicotine pouches while researchers measure their exposure to harmful …

This study tests whether a mild, non-invasive brain stimulation technique called tDCS can reduce tobacco cravings and help people smoke less. About 100 adults who are dependent on nicotine will receive either real or fake tDCS sessions alongside standard counseling. The goal is t…

This study tests whether a daily oral dose of cannabidiol (CBD) can help people stop smoking tobacco. Fifty adults who smoke more than 10 cigarettes a day and want to quit will take CBD during several practice quit attempts. The goal is to see if CBD increases short-term abstinen…

This study looks at whether yoga can help people who want to quit tobacco by reducing their cravings. About 96 men who are dependent on tobacco will either do yoga or receive standard quitting advice. Researchers will check cravings and relapse rates over three months to see if y…

This study tests whether cannabidiol (CBD) can help people who want to quit smoking reduce their cigarette use. Researchers will give 120 adults with tobacco use disorder either CBD or a placebo twice daily for 56 days. They will measure nicotine levels, cravings, and withdrawal …