SUBSTANCE USE DISORDERS
Clinical trials for SUBSTANCE USE DISORDERS explained in plain language.
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New approach to starting opioid addiction treatment avoids withdrawal
Disease control TerminatedThis study tested a new method for starting buprenorphine (a medication for opioid use disorder) that avoids the usual withdrawal symptoms. Instead of stopping all opioids first, patients started with very low doses of buprenorphine while still taking their regular opioids. The s…
Matched conditions: SUBSTANCE USE DISORDERS
Phase: PHASE4 • Sponsor: Montefiore Medical Center • Aim: Disease control
Last updated May 18, 2026 11:59 UTC
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New approach to HIV prevention for LGBTQ+ substance users falls short
Prevention TerminatedThis study aimed to help HIV-negative transgender women and men who have sex with men who also have a substance use disorder stick with PrEP (HIV prevention medication). Participants were given counseling and text support, with extra help for those struggling. The study was termi…
Matched conditions: SUBSTANCE USE DISORDERS
Phase: NA • Sponsor: Friends Research Institute, Inc. • Aim: Prevention
Last updated May 26, 2026 03:54 UTC
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Magic mushroom compound studied for meth addiction – but study halted early
Symptom relief TerminatedThis study looked at whether psilocybin, the active ingredient in magic mushrooms, is safe and practical to use alongside behavioral support for people with methamphetamine use disorder. Only 5 participants were enrolled before the study was stopped early. The main goal was to tr…
Matched conditions: SUBSTANCE USE DISORDERS
Phase: PHASE1 • Sponsor: University of Wisconsin, Madison • Aim: Symptom relief
Last updated May 26, 2026 03:55 UTC