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New approach lets patients start addiction treatment without first going through withdrawal

NCT ID NCT05118204

First seen Nov 01, 2025 · Last updated Jun 18, 2026 · Updated 33 times

Summary

This study tested a new method for starting buprenorphine (a medication for opioid use disorder) in hospitalized adults who also have chronic pain. Instead of requiring patients to stop all other opioids and go through withdrawal first, the new method starts with very low doses of buprenorphine while continuing other opioids. The study enrolled 23 adults and compared this microdose approach to the standard method, looking at how many patients successfully started buprenorphine treatment.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Montefiore Medical Center

    The Bronx, New York, 10467, United States

Conditions

The condition(s) this trial relates to.

Chronic Pain chronic pain syndrome opiate dependence substance-related disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.