SQUAMOUS CELL CARCINOMA OF THE HEAD AND NECK
Clinical trials for SQUAMOUS CELL CARCINOMA OF THE HEAD AND NECK explained in plain language.
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New combo therapy aims to tame head and neck cancer with fewer side effects
Disease control CompletedThis study tested a three-step treatment for head and neck cancer: chemotherapy before surgery, then surgery, followed by more chemo and radiation based on risk. The goal was to see if this approach could reduce side effects and improve how well the treatment works. 40 adults wit…
Matched conditions: SQUAMOUS CELL CARCINOMA OF THE HEAD AND NECK
Phase: PHASE2 • Sponsor: UNC Lineberger Comprehensive Cancer Center • Aim: Disease control
Last updated May 26, 2026 12:12 UTC
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Radiation boosts immunotherapy in advanced cancers?
Disease control CompletedThis study tested whether a short course of radiation to one tumor site could make immunotherapy work better in people with advanced lung or head/neck cancer. 76 participants received radiation within two weeks of starting their first immunotherapy dose. The main goal was to see …
Matched conditions: SQUAMOUS CELL CARCINOMA OF THE HEAD AND NECK
Phase: PHASE2 • Sponsor: John L. Villano, MD, PhD • Aim: Disease control
Last updated May 26, 2026 12:12 UTC
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MRI-Guided radiation boosts cancer fight in advanced head and neck tumors
Disease control CompletedThis study tested a new way to give radiation therapy to people with advanced head and neck cancer. Doctors used a special MRI scan to find parts of the tumor that are most resistant to standard radiation and gave those areas a higher dose, while keeping normal doses to healthy t…
Matched conditions: SQUAMOUS CELL CARCINOMA OF THE HEAD AND NECK
Phase: PHASE2 • Sponsor: University of Michigan Rogel Cancer Center • Aim: Disease control
Last updated May 26, 2026 12:11 UTC
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New drug combos show promise in shrinking head and neck tumors before surgery
Disease control CompletedThis study tested several drug combinations in 12 people with advanced head and neck cancer that had not been treated yet. The goal was to see if the drugs could make tumors disappear or shrink before surgery. The study is now complete, and the results help guide future treatment…
Matched conditions: SQUAMOUS CELL CARCINOMA OF THE HEAD AND NECK
Phase: PHASE1, PHASE2 • Sponsor: Hoffmann-La Roche • Aim: Disease control
Last updated May 26, 2026 12:10 UTC
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Immune cell combo shows promise in tough head and neck cancers
Disease control CompletedThis early-phase study tested a new treatment combining immune-boosting drugs with specially trained natural killer (NK) cells in 11 people with advanced head and neck cancer that had returned or spread. The goal was to see if the combination was safe and could shrink tumors. Whi…
Matched conditions: SQUAMOUS CELL CARCINOMA OF THE HEAD AND NECK
Phase: PHASE1 • Sponsor: Dana-Farber Cancer Institute • Aim: Disease control
Last updated May 26, 2026 12:10 UTC
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New drug combo shows promise for Tough-to-Treat cancers
Disease control CompletedThis study tested whether combining two drugs, brentuximab vedotin and pembrolizumab, can shrink tumors in people with advanced melanoma, lung cancer, or head and neck cancer that has spread. About 161 participants took part. The goal was to see how many patients had their tumors…
Matched conditions: SQUAMOUS CELL CARCINOMA OF THE HEAD AND NECK
Phase: PHASE2 • Sponsor: Seagen, a wholly owned subsidiary of Pfizer • Aim: Disease control
Last updated May 26, 2026 12:00 UTC
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New drug combo aims to stop head and neck cancer from returning
Disease control CompletedThis early-phase study tested the safety of adding the drug afatinib to standard radiation (with or without chemo) for people with intermediate- or high-risk head and neck cancer after surgery. Afatinib blocks proteins that help cancer grow and may make cancer cells more sensitiv…
Matched conditions: SQUAMOUS CELL CARCINOMA OF THE HEAD AND NECK
Phase: PHASE1 • Sponsor: Dana-Farber Cancer Institute • Aim: Disease control
Last updated May 26, 2026 11:09 UTC
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Immunotherapy drug may keep high-risk head and neck cancer at bay
Disease control CompletedThis study tested whether giving the immunotherapy drug pembrolizumab for one year after standard treatment could delay cancer recurrence in 100 patients with high-risk head and neck cancer. Half received pembrolizumab and half received a placebo. The main goal was to see how lon…
Matched conditions: SQUAMOUS CELL CARCINOMA OF THE HEAD AND NECK
Phase: PHASE2 • Sponsor: University of Chicago • Aim: Disease control
Last updated May 22, 2026 14:04 UTC
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Last-Resort drug shows promise for tough head and neck cancers
Disease control CompletedThis study tested a chemotherapy drug called mitomycin C in 48 adults with advanced head and neck cancer that had stopped responding to standard treatments. The goal was to see if the drug could shrink tumors. The trial focused on two groups: patients with HPV-related tonsil/base…
Matched conditions: SQUAMOUS CELL CARCINOMA OF THE HEAD AND NECK
Phase: PHASE2 • Sponsor: Washington University School of Medicine • Aim: Disease control
Last updated May 19, 2026 12:01 UTC
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New drug combo shows promise for incurable head and neck cancer
Disease control CompletedThis early-phase trial tested a combination of two drugs (IRX-2 regimen and durvalumab) in 19 patients with advanced head and neck cancer that could not be cured with standard treatments. The main goals were to check safety and see if the drugs could boost the immune response ins…
Matched conditions: SQUAMOUS CELL CARCINOMA OF THE HEAD AND NECK
Phase: PHASE1 • Sponsor: H. Lee Moffitt Cancer Center and Research Institute • Aim: Disease control
Last updated May 18, 2026 12:12 UTC
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Immunotherapy shows promise in shrinking head and neck tumors before surgery
Disease control CompletedThis study tested whether giving the immunotherapy drug pembrolizumab (MK-3475) before standard surgery could help prevent head and neck cancer from coming back. It included 67 adults with advanced, surgically removable head and neck cancer. The main goal was to see if the drug c…
Matched conditions: SQUAMOUS CELL CARCINOMA OF THE HEAD AND NECK
Phase: PHASE2 • Sponsor: Washington University School of Medicine • Aim: Disease control
Last updated May 13, 2026 16:02 UTC
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Tailored immunotherapy shows promise for tough head and neck cancers
Disease control CompletedThis study tested a personalized approach to immunotherapy in 20 people with advanced head and neck cancer that had already worsened after standard immunotherapy. Researchers used genetic testing of the tumor to choose which additional drug to add to the standard treatment, aimin…
Matched conditions: SQUAMOUS CELL CARCINOMA OF THE HEAD AND NECK
Phase: PHASE2 • Sponsor: Dan Zandberg • Aim: Disease control
Last updated May 13, 2026 16:01 UTC
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Home diet advice may boost Well-Being during cancer radiation
Symptom relief CompletedThis study looked at whether having a dietitian visit patients at home during radiation therapy could improve their quality of life. It included 117 adults with head and neck cancer who were starting radiotherapy. The goal was to see if personalized nutrition support helps patien…
Matched conditions: SQUAMOUS CELL CARCINOMA OF THE HEAD AND NECK
Phase: NA • Sponsor: University Hospital, Caen • Aim: Symptom relief
Last updated May 26, 2026 12:03 UTC
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New study aims to reduce dry mouth from head and neck cancer radiation
Symptom relief CompletedThis study looked at two different ways to plan radiation therapy for head and neck cancer to see which causes less dry mouth. 23 patients took part, and researchers measured their dry mouth symptoms and quality of life. The goal was to find a planning method that reduces this co…
Matched conditions: SQUAMOUS CELL CARCINOMA OF THE HEAD AND NECK
Phase: NA • Sponsor: University of Arkansas • Aim: Symptom relief
Last updated May 26, 2026 11:09 UTC
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New study asks skin cancer patients: are you happy with your care?
Knowledge-focused CompletedThis study looked at how people with a serious type of skin cancer on the head or neck feel about their treatment decisions, quality of life, and satisfaction with care. Researchers asked 78 patients to fill out questionnaires about their health, worries, and how supported they f…
Matched conditions: SQUAMOUS CELL CARCINOMA OF THE HEAD AND NECK
Sponsor: Maastricht University Medical Center • Aim: Knowledge-focused
Last updated May 22, 2026 13:52 UTC