SOLID TUMORS, ADULT
Clinical trials for SOLID TUMORS, ADULT explained in plain language.
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New drug targets tough cancers in 401-Patient trial
Disease control Recruiting nowThis study tests a new drug, ABSK141, in about 401 adults with advanced solid tumors that have a specific gene change called KRAS G12D. The goal is to find the best dose and check if it is safe and works against cancers like colorectal, lung, and pancreatic cancer. Participants w…
Matched conditions: SOLID TUMORS, ADULT
Phase: PHASE1, PHASE2 • Sponsor: Abbisko Therapeutics Co, Ltd • Aim: Disease control
Last updated May 01, 2026 16:00 UTC
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New combo targets Hard-to-Treat cancers with STK11 mutation
Disease control Recruiting nowThis study tests an experimental drug called TNG260 combined with an immunotherapy (pembrolizumab) in people with advanced solid tumors that have a specific genetic change (STK11 mutation). The goal is to find the best dose and see if the combination is safe and can shrink tumors…
Matched conditions: SOLID TUMORS, ADULT
Phase: PHASE1, PHASE2 • Sponsor: Tango Therapeutics, Inc. • Aim: Disease control
Last updated Apr 30, 2026 15:50 UTC
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New cancer drug candidate DCR-PDL1 enters first human safety trial
Disease control Recruiting nowThis study is testing a new drug called DCR-PDL1 in adults with advanced solid tumors that have not responded to standard treatments. The main goal is to check the drug's safety and how the body processes it. Participants will receive increasing doses of the drug through an IV to…
Matched conditions: SOLID TUMORS, ADULT
Phase: PHASE1 • Sponsor: Dicerna Pharmaceuticals, Inc., a Novo Nordisk company • Aim: Disease control
Last updated Apr 30, 2026 15:49 UTC
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Immune cells from your own tumor could fight cancer – early trial launches
Disease control Recruiting nowThis early-phase study tests a personalized cell therapy (TIL injection) for people with advanced solid tumors that have spread or come back. Doctors take immune cells from a patient's own tumor, grow them in a lab, and infuse them back after mild chemotherapy. The main goal is t…
Matched conditions: SOLID TUMORS, ADULT
Phase: PHASE1 • Sponsor: Grit Biotechnology • Aim: Disease control
Last updated Apr 29, 2026 15:15 UTC
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New smart chemo targets HER-2 cancers in early trial
Disease control Recruiting nowThis early-phase study tests a new drug, HF158K1, which delivers chemotherapy directly to cancer cells that have a protein called HER-2. The trial includes about 84 adults with advanced solid tumors that cannot be removed by surgery or have spread. The main goals are to check the…
Matched conditions: SOLID TUMORS, ADULT
Phase: PHASE1 • Sponsor: HighField Biopharmaceuticals Corporation • Aim: Disease control
Last updated Apr 29, 2026 15:15 UTC
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New drug targets mutations in Hard-to-Treat cancers
Disease control Recruiting nowThis study tests a new drug, STX-478, in people with advanced solid tumors (like breast cancer) that have a specific genetic change called PI3Kα mutation. The drug is given alone or with other cancer treatments. The goal is to see if it is safe and helps shrink tumors. About 880 …
Matched conditions: SOLID TUMORS, ADULT
Phase: PHASE1, PHASE2 • Sponsor: Eli Lilly and Company • Aim: Disease control
Last updated Apr 29, 2026 15:05 UTC