SOLID TUMORS, ADULT
Clinical trials for SOLID TUMORS, ADULT explained in plain language.
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New drug HMPL-A580 tested in advanced cancer patients
Disease control Recruiting nowThis study tests a new drug called HMPL-A580 in adults with advanced solid tumors that cannot be removed by surgery. The goal is to find the safest dose and see if it helps shrink tumors. About 186 participants will take part in this early-phase trial.
Matched conditions: SOLID TUMORS, ADULT
Phase: PHASE1, PHASE2 • Sponsor: Hutchmed • Aim: Disease control
Last updated Jun 16, 2026 23:39 UTC
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New drug HMPL-A251 tested in advanced HER2 cancers – first human trial begins
Disease control Recruiting nowThis study tests a new drug called HMPL-A251 in adults with advanced or metastatic solid tumors that have a protein called HER2. The main goals are to find a safe dose and see if the drug can shrink tumors. About 147 participants will receive the drug, and researchers will monito…
Matched conditions: SOLID TUMORS, ADULT
Phase: PHASE1, PHASE2 • Sponsor: Hutchmed • Aim: Disease control
Last updated Jun 16, 2026 23:36 UTC
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Immune cells take on tough tumors in early trial
Disease control Recruiting nowThis early-stage trial tests a personalized cell therapy (TIL injection) for people with advanced solid tumors that have spread or come back. The treatment uses the patient's own immune cells, grown in a lab, to fight the cancer. The main goal is to check safety, and the study wi…
Matched conditions: SOLID TUMORS, ADULT
Phase: PHASE1 • Sponsor: Grit Biotechnology • Aim: Disease control
Last updated Jun 15, 2026 19:04 UTC
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New drug targets tough cancers with KRAS G12D mutation
Disease control Recruiting nowThis study tests an experimental drug called ABSK141 in people with advanced solid tumors that have a specific genetic change called KRAS G12D. The main goals are to check the drug's safety, find the best dose, and see if it helps shrink tumors. About 401 adults with cancers like…
Matched conditions: SOLID TUMORS, ADULT
Phase: PHASE1, PHASE2 • Sponsor: Abbisko Therapeutics Co, Ltd • Aim: Disease control
Last updated Jun 15, 2026 18:57 UTC
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New hope for hard-to-treat cancers: experimental combo targets STK11 mutation
Disease control Recruiting nowThis study tests an experimental drug called TNG260 combined with an immunotherapy (pembrolizumab) in people with advanced solid tumors that have a specific gene change (STK11 mutation). The goal is to find the best dose and see if the combination is safe and can shrink tumors. A…
Matched conditions: SOLID TUMORS, ADULT
Phase: PHASE1, PHASE2 • Sponsor: Tango Therapeutics, Inc. • Aim: Disease control
Last updated Jun 15, 2026 18:57 UTC
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New smart chemo targets HER-2 cancers in early trial
Disease control Recruiting nowThis early-phase study tests HF158K1, a chemotherapy drug wrapped in a special coating that targets HER-2, a protein on some cancer cells. The goal is to see if it is safe and can shrink tumors in people with advanced solid tumors that have not responded to other treatments. Abou…
Matched conditions: SOLID TUMORS, ADULT
Phase: PHASE1 • Sponsor: HighField Biopharmaceuticals Corporation • Aim: Disease control
Last updated Jun 12, 2026 12:07 UTC
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New cancer drug DCR-PDL1 enters first human safety tests
Disease control Recruiting nowThis early-stage study is testing a new drug called DCR-PDL1 in about 32 adults with solid tumors that have not responded to standard treatments. The main goal is to check the drug's safety and find the right dose by giving it through an IV and watching for side effects. This is …
Matched conditions: SOLID TUMORS, ADULT
Phase: PHASE1 • Sponsor: Dicerna Pharmaceuticals, Inc., a Novo Nordisk company • Aim: Disease control
Last updated Jun 11, 2026 12:12 UTC
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New drug targets mutant cancers in early trial
Disease control Recruiting nowThis study tests a new drug, STX-478, in people with advanced solid tumors that have a specific genetic mutation (PI3Kα). The drug is given alone or with other cancer treatments. The goal is to see if it is safe and shrinks tumors. About 880 adults with breast cancer or other sol…
Matched conditions: SOLID TUMORS, ADULT
Phase: PHASE1, PHASE2 • Sponsor: Eli Lilly and Company • Aim: Disease control
Last updated Jun 10, 2026 13:28 UTC
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Immune cells from your own tumor: a new hope for advanced cancer?
Disease control Recruiting nowThis early-phase study tests a personalized treatment called GT101 for adults with advanced solid tumors that have spread or come back. Doctors take immune cells from the patient's own tumor, grow them in a lab, and infuse them back after mild chemotherapy. The goal is to see if …
Matched conditions: SOLID TUMORS, ADULT
Phase: PHASE1 • Sponsor: Grit Biotechnology • Aim: Disease control
Last updated Jun 09, 2026 12:10 UTC
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New scan could spot hidden cancers
Diagnosis Recruiting nowThis study tests a new radioactive tracer called FAP-2286 to see if it can better detect cancer that has spread in adults with solid tumors. About 191 participants will receive the tracer and then have a PET scan. The goal is to measure how safe the tracer is and how well it find…
Matched conditions: SOLID TUMORS, ADULT
Phase: PHASE1 • Sponsor: Thomas Hope • Aim: Diagnosis
Last updated Jun 16, 2026 23:37 UTC