SKIN CANCER

This early study tested a new way of giving three drugs (encorafenib, binimetinib, and nivolumab) to people with advanced BRAF-mutant melanoma. The goal was to see if an on/off schedule could help control the cancer while reducing side effects. Only 14 adults with stage IIIC to I…

This study tests whether combining radiation therapy with the immunotherapy drug cemiplimab can help people with a type of advanced skin cancer called cutaneous squamous cell carcinoma that cannot be removed by surgery. About 34 participants will receive this treatment to see if …

This study tests whether adding a precise type of radiation (SBRT) to a two-drug immunotherapy combination (nivolumab and ipilimumab) works better than the drugs alone for people with advanced Merkel cell carcinoma, a rare and aggressive skin cancer. About 50 adults whose cancer …

This study tests a new treatment called DaRT, where tiny devices that give off a special type of radiation (alpha rays) are placed directly into tumors. It is for people with skin cancer, mouth cancer, or soft tissue cancer that has not responded to standard treatments or who can…

This early-phase study tests a new drug, XL888, added to two existing melanoma drugs (vemurafenib and cobimetinib) for people with advanced BRAF-mutated melanoma that cannot be removed by surgery. The main goal is to find the safest dose of XL888 and see how well the combination …

This study tests a new, non-invasive imaging technique that uses a special microscope to look at skin lesions in detail without cutting the skin. The goal is to improve early detection of skin cancer and reduce the number of biopsies needed. Over 1,800 people with skin lesions an…

This study tests a new imaging method called photoacoustic imaging to see skin tumors in three dimensions. Researchers will compare the images to standard lab results from surgery. The goal is to improve how doctors measure tumor depth and borders without extra procedures.

This phase 3 trial tests whether a cream containing sirolimus, applied nightly for 24 weeks, can prevent facial skin cancers in people who have received an organ transplant. The study includes 146 adults who have had a transplant at least a year ago and have a history of skin can…

This study planned to use online tools like ads and social media to encourage people to avoid risky behaviors that can lead to skin cancer, such as indoor tanning. It aimed to reach adult men on Facebook who were interested in the LGBT community. However, the study was withdrawn …

This study asks 3000 adults who had skin cancer surgery to fill out a one-time online survey about how they feel about their appearance, scars, and quality of life. The goal is to learn what matters most to patients after surgery. No new treatments are being tested.

This study collects fresh tumor samples from 416 adults with various cancers (bladder, kidney, colorectal, head and neck, liver, lung, skin, endometrial) to develop and train a live tumor diagnostic platform. The goal is to see how accurately the platform can predict whether a pa…

This pilot study tests a community-based educational program to raise awareness of melanoma and other skin cancers. About 45 adults in Brooklyn will attend a session led by a health worker and complete surveys and follow-ups over 12 months. The goal is to see if the program impro…