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Transplant patients get new hope: cream may stop skin cancer before it starts

NCT ID NCT05860881

First seen Nov 01, 2025 · Last updated May 23, 2026 · Updated 30 times

Summary

This phase 3 trial tests whether a cream containing sirolimus, applied nightly for 24 weeks, can prevent facial skin cancers in people who have received an organ transplant. The study includes 146 adults who have had a transplant at least a year ago and have a history of skin cancer. The main goal is to see if the cream reduces the number of new skin cancers compared to a placebo cream over two years.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Princess Alexandra Hospital

    Woolloongabba, Queensland, 4102, Australia

  • Royal Prince Alfred Hospital

    Camperdown, New South Wales, 2050, Australia

  • Skin Health Institute

    Carlton, Victoria, 3053, Australia

  • The Alfred Hospital

    Melbourne, Victoria, 3004, Australia

  • The Prince Charles Hospital

    Chermside, Queensland, 4032, Australia

  • Westmead Hospital

    Westmead, New South Wales, 2145, Australia

Conditions

Explore the condition pages connected to this study.