SEPTIC SHOCK
Clinical trials for SEPTIC SHOCK explained in plain language.
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Dialysis timing in septic shock: early vs. delayed – which saves more lives?
Disease control TerminatedThis study looked at 500 adults in intensive care with septic shock and severe kidney failure. It compared starting dialysis early (within 12 hours) versus waiting 48-60 hours to see if timing affected survival at 90 days. The trial was terminated early, so results are limited.
Matched conditions: SEPTIC SHOCK
Phase: PHASE3 • Sponsor: Centre Hospitalier Universitaire Dijon • Aim: Disease control
Last updated May 26, 2026 05:27 UTC
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Kidney-Sparing strategy in sepsis put to the test – but study stopped early
Disease control TerminatedThis study tested whether using a urine biomarker test (NephroCheck) to guide kidney-protective care could reduce deaths, need for dialysis, or worsening kidney injury in sepsis patients. The trial planned to enroll adults with sepsis in the ICU, but was terminated early after on…
Matched conditions: SEPTIC SHOCK
Phase: NA • Sponsor: BioMérieux • Aim: Disease control
Last updated May 26, 2026 05:26 UTC
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Kidney-Smart blood pressure strategy tested in septic shock patients
Disease control TerminatedThis study tested whether setting a patient's blood pressure target based on kidney ultrasound readings could prevent acute kidney injury during septic shock. Researchers enrolled 27 adults with septic shock and compared personalized blood pressure management to standard care. Th…
Matched conditions: SEPTIC SHOCK
Phase: NA • Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Disease control
Last updated May 22, 2026 14:02 UTC
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Could a common sedative save lives in septic shock?
Disease control TerminatedThis study tested whether a sedative called dexmedetomidine could help restore blood pressure response in adults with severe septic shock who were not responding to standard treatments. The trial was stopped early, but it aimed to see if the drug could improve how the body reacts…
Matched conditions: SEPTIC SHOCK
Phase: PHASE3 • Sponsor: Centre Hospitalier Universitaire Dijon • Aim: Disease control
Last updated May 22, 2026 13:53 UTC
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Septic shock drug trial halted early: Midodrine's promise unfulfilled
Disease control TerminatedThis study tested whether the oral drug midodrine could help patients with septic shock get off IV blood pressure medications faster. Only 10 people participated before the trial was stopped early. The goal was to see if midodrine could reduce time on IV drugs and shorten hospita…
Matched conditions: SEPTIC SHOCK
Phase: PHASE3 • Sponsor: University of Virginia • Aim: Disease control
Last updated May 20, 2026 11:57 UTC
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New sedation approach may help septic shock patients breathe on their own sooner
Symptom relief TerminatedThis study tested whether a gas sedative (isoflurane) helps patients with septic shock wake up and get off a breathing machine faster than standard IV sedation (midazolam). The trial was planned for adults in the ICU needing sedation for 3-28 days. However, the study was stopped …
Matched conditions: SEPTIC SHOCK
Phase: PHASE4 • Sponsor: University Hospital, Rouen • Aim: Symptom relief
Last updated May 22, 2026 13:53 UTC