SAFETY

This early-phase study tested a personalized therapy where immune cells are taken from a patient's own tumor, grown in large numbers in a lab, and then infused back into the patient. The goal was to see if this treatment is safe and can shrink advanced solid tumors like melanoma,…

This study tested if injecting the antifungal drug fluconazole directly into the cornea is safe and effective for treating fungal keratitis, a serious eye infection. 40 patients with lab-confirmed fungal infections that were sensitive to fluconazole took part. The researchers mea…

This study tested a treatment called GC101 TIL for people with advanced melanoma that had stopped responding to standard therapies. Doctors took immune cells from each patient's own tumor, multiplied them in a lab, and gave them back to the patient. The goal was to see if this ap…

This study tested a new daily supplement called KGA-10 (a heat-killed bacterium) in 107 healthy adults to see if it could lower stress, reduce inflammation, and improve sleep and general well-being. Participants took either the supplement or a placebo for 8 weeks and completed su…

This study looked at whether taking a dietary supplement for 60 days could improve thinking skills and mood in 75 university students. Participants were split into three groups: two received different supplements, and one got a placebo. Researchers measured changes in self-confid…

This study tested a numbing injection given around both eyes to see if it safely controls pain during cataract surgery. Fifty adults received the injection, and researchers measured their pain and satisfaction. The goal was to find a better way to keep patients comfortable during…

This completed trial tested whether a heat-killed bacterium called KGA-10 (NeuroAlly) is safe and tolerable for healthy adults. Eight participants took either KGA-10 or a placebo daily for one week. Researchers tracked side effects and satisfaction using surveys. The study was ve…

This early-stage study tested a single dose of the experimental drug Y-3 in 20 healthy adults to see if it is safe and how the body processes it. Participants received either 40 mg, 60 mg, or a placebo. The study is complete and focused on gathering basic safety and drug-level in…

This study looked at whether it is safe for pregnant women to receive the mRNA COVID-19 vaccine and the flu shot at the same time versus a few weeks apart. 98 pregnant women were randomly assigned to one of the two schedules. Researchers tracked side effects, pregnancy outcomes, …

This study tested whether giving the drug pasireotide with a reusable pen works as well as using a traditional syringe. Forty healthy adults received a single dose by both methods to compare how the drug enters the body and if it is safe. The goal is to find a more convenient way…

This study tested a new micellar form of the antioxidant glutathione in 16 healthy adults. Researchers compared how well it was absorbed versus standard and liposomal glutathione capsules over 30 days. The goal was to see if the new formulation leads to higher levels in the blood…

This study tested an online tool called 'Safety in Dementia' that guides caregivers of people with dementia through decisions about firearm access. 500 caregivers across the US used the tool or a standard safety checklist. The goal was to see if the tool helps caregivers feel mor…

This study tested a community bike safety program for 195 kids ages 9 to 12. Some kids took a 12-hour safety class, some took the class plus a parent training session, and others received no training. All bikes were equipped with GPS and video cameras to track real-world riding b…

This study checked whether a specific oral probiotic (Streptococcus salivarius eK12) is safe for healthy adults to take. A total of 29 participants in Pakistan and Italy received the probiotic or a placebo. Researchers monitored for side effects and changes in vital signs, blood …

This study looked at how safe kratom is and how the body processes it in healthy adults who have used opioids recreationally. 40 participants received single rising doses of kratom to monitor side effects and drug levels. The goal was to gather basic safety information, not to tr…

This early-stage study tested whether a purified exosome product (PEP) is safe when injected into the skin of healthy adults. Eight participants received the injection and were monitored for side effects. The goal was to check for any immediate reactions or lab changes, not to tr…

This study tested a new way to teach personal safety to 60 children aged 4-5. Half of the kids took part in a special program using games and activities based on multiple intelligences theory, while the other half had regular lessons. The program aimed to improve children's knowl…