SAFETY

This early-stage trial tested a therapy made from a patient's own immune cells (tumor-infiltrating lymphocytes) to fight advanced solid tumors like melanoma, cervical cancer, and lung cancer. 43 adults participated to find the safest dose and check for side effects. The goal was …

This study looked at whether it's safe for pregnant women to receive the COVID-19 and flu vaccines at the same time or a week or two apart. About 100 pregnant women took part, and researchers tracked side effects and pregnancy outcomes like preterm birth. The goal was to find the…

This study looked at whether giving a numbing injection around both eyes (called a bilateral peribulbar block) is safe and works well for cataract surgery. Fifty adults having cataract surgery received the injection, and researchers measured their pain during the procedure and ho…

This study tested whether giving the drug pasireotide with a reusable pen works as well and is as safe as using a traditional syringe. Forty healthy adults aged 18 to 55 each received the drug by both methods on separate days. The goal was to see how the body absorbs the drug and…

This study looked at the safety and effects of kratom, a plant sometimes used for pain or opioid withdrawal, in 40 healthy adults who have used opioids recreationally but are not dependent. Participants received single increasing doses of kratom to see how the body processes it a…

This early-stage study checked whether a purified exosome product (PEP) is safe when injected into the skin of 8 healthy adults. Each person served as their own control, comparing PEP to a placebo. The goal was only to measure side effects and tolerability, not to treat any disea…