SAFETY

This study tests a new stem cell therapy called XS228 for people with recent spinal cord injuries. The treatment uses lab-made nerve cells injected into the spinal fluid to help repair damage. About 60 adults with incomplete paralysis will receive either XS228 or a placebo and be…

This study looks at whether a program called Safe Night Out, which trains bar staff to spot and stop sexual and intimate partner violence, actually works. Researchers will enroll 150 staff and 500 patrons from 50 bars in California. Half the bars use the program, half do not. Par…

This study compares a new dressing called POLTX_Fiber to a standard one (Suprasorb Liquacel Pro) for chronic wounds like leg ulcers and pressure sores. About 60 adults with moderate-to-heavy wound drainage will be followed for 30 days. Researchers will track wound healing, infect…

This study tests a nasal spray containing dexmedetomidine to help patients relax before surgery, even with minimal monitoring. Researchers will compare it to a placebo in 564 adults to see if it causes fewer breathing or heart problems. The goal is to find a safer, easier way to …

This Phase 1 trial tests the safety and tolerability of a new oral drug called YR011 in 64 healthy volunteers. The drug blocks a potassium channel involved in immune cell activity. Participants receive either YR011 or a placebo in single or multiple doses. The study aims to find …

This study looks at whether nurses' attitudes about safety in a day surgery unit are linked to how safe patients feel during their procedure. About 206 people—half nurses and half patients—will take surveys before and after surgery. The goal is to understand if a strong safety cu…

This study tests whether a website called the Family Safety Check-In can help families with children store their firearms more safely. About 548 parents or guardians who have guns at home and currently store them unsafely will be randomly assigned to use the website or not. The g…