RENAL IMPAIRMENT

This study is testing a new medical device designed to protect kidney function in patients with existing kidney problems who need heart surgery. The device, called JuxtaFlow, works by gently supporting the kidneys' natural filtering process during the stressful period of surgery.…

This early-stage study aims to understand how a new drug called eloralintide behaves in people with severe kidney problems compared to healthy people. Researchers will give a single injection to 28 participants and track how much drug gets into their blood and how long it stays. …

This early-stage study aims to understand how a new drug called MK-2828 is processed by the body in people with impaired kidney function. Researchers will compare blood levels of the drug in 24 participants—some with kidney disease and some healthy—after they receive one or two d…

This early-stage study aims to understand how kidney function affects the way a new drug called enpatoran moves through the body. Researchers will compare a single dose in 40 people with normal kidney function to those with impaired kidney function. The main goal is to measure dr…

This early-stage study aims to understand how a single dose of a new antiviral drug combination is processed by the body in people with severe liver or kidney impairment. It will compare the drug's levels and safety in these participants to a matched group of healthy volunteers. …

This early-stage study aims to understand how a new oral medicine called PF-07328948 is processed by the body in people with different levels of kidney function. It will enroll 28 adults, including both healthy participants and those with moderate to severe long-term kidney impai…

This early-stage study aims to understand how a new drug, opemalirsen, is processed by the body in people with different levels of kidney function compared to people with normal kidney function. About 50 adults, some with kidney impairment and some without, will receive a single …

This early-stage study aims to understand how a new drug, S-892216, behaves in the body of people with different levels of kidney function. It will enroll 40 participants, some with healthy kidneys and some with mild to severe kidney problems, including some on dialysis. The main…

This is an early safety study to understand how a new drug, LY3537031, moves through and leaves the body. It will compare people with healthy kidney function to those with severe kidney impairment or kidney failure. The main goal is to measure drug levels in the blood and check f…