PULMONARY EMBOLISM

This study tests whether using a patient's gender, weight, and kidney function to calculate the first dose of the blood thinner heparin helps reach the target level faster than using a standard dose based only on weight. About 145 adults with conditions like deep vein thrombosis,…

This study tests a device that removes blood clots from the lungs of people with acute pulmonary embolism (a sudden blockage in lung arteries). About 125 adults with severe symptoms will be treated, and doctors will check if the device safely improves heart function within 48 hou…

This study compares two types of breathing support—high-flow nasal cannula and non-invasive ventilation—for people with acute respiratory failure caused by a pulmonary embolism (a blood clot in the lungs). The goal is to see which method helps patients breathe on their own more s…

This study tests a new device called the Aventus Thrombectomy System to safely remove blood clots from the lungs in people with acute pulmonary embolism. About 130 adults aged 18 to 80 with recent clot symptoms will be treated. The goal is to see if the device improves heart func…

This study compares two treatments for people with a serious type of blood clot in the lungs (pulmonary embolism). Half of the 544 participants will receive standard blood thinners, while the other half will get blood thinners plus a special device that uses ultrasound to help di…

This study tests a new way to treat pulmonary embolism (blood clots in the lungs) using a low dose of clot-busting medicine delivered through a thin tube guided by ultrasound. About 60 adults with moderate to severe clots will receive this treatment to see if it safely improves b…

This study tests whether personalizing the length of blood thinner treatment after a first blood clot can prevent future clots while reducing bleeding risks. Over 600 adults who had a first clot filled out a questionnaire and provided a cheek swab to estimate their individual ris…

This study looks at why blood clots form in the legs (venous thrombosis) and lungs (pulmonary embolism) in over 21,000 African American and white adults. Researchers are using data from two long-running health studies to find risk factors. The goal is to better understand these c…

This study was designed to test if a non-invasive blood pressure monitor could measure how well the heart is pumping in people with a pulmonary embolism (a blood clot in the lungs). The goal was to see if these measurements could help doctors predict which patients are at risk of…

This study is looking for genetic clues that might explain why some people develop a dangerous blood clot in the lung (pulmonary embolism) after hip or knee replacement surgery. Researchers will collect blood samples from 100 adults who have had this complication in the past and …

This study looks at how a first-time blood clot in the leg or lung affects exercise ability and shortness of breath in children and teens aged 8 to 21. Researchers will measure changes in exercise capacity and breathing using special tests. The goal is to better understand these …

This study aimed to see if breathing in nitric oxide gas could improve blood flow in the lungs of people with a serious pulmonary embolism (a blood clot in the lung). It planned to include 20 adults at one hospital, measuring heart and lung pressures before, during, and after the…