PRIMARY DYSMENORRHEA

This study tests whether women aged 18-30 with painful periods can reduce their pain and premenstrual symptoms by pressing on specific body points themselves (self-acupressure). Half the 120 participants will learn real acupressure points, the other half will use sham points. The…

This study tests a simple, non-invasive treatment called transcutaneous tibial nerve stimulation (TTNS) for period pain. It involves 32 women aged 20-25 with primary dysmenorrhea. The goal is to see if this nerve stimulation can reduce pain and improve quality of life.

This study tests whether doing yoga and cognitive exercise therapy from home (via telerehabilitation) can reduce pain and improve physical function and quality of life in adolescent girls with primary dysmenorrhea (painful periods). About 42 teens aged 10–19 will participate. The…

This study tests whether injecting botulinum toxin (Botox) into the uterine muscle can reduce severe period pain in women who haven't gotten relief from standard treatments like painkillers or hormones. About 222 adult women with severe primary dysmenorrhea will receive either Bo…

This study looks at whether adding motor imagery (mental practice of movement) or pain neuroscience education (learning about how pain works) to an exercise program can reduce menstrual pain and improve thinking flexibility in young women with primary dysmenorrhea. About 51 women…

This study tests a new medicine called CDE100 to see if it safely reduces menstrual cramp pain in women with primary dysmenorrhea (painful periods without an underlying condition). About 238 women aged 16 to 35 with moderate to severe cramps will take the drug or a placebo during…

This study looks at whether period pain affects how well young women sense their knee position and maintain balance. Researchers will measure balance and knee joint awareness in 62 healthy female students aged 18-25 who have regular periods. The goal is to understand if menstrual…