PRIMARY ALDOSTERONISM

This study is testing whether a minimally invasive procedure called superselective adrenal artery embolization works as well as or better than standard medication (spironolactone) for people with primary aldosteronism, a hormone condition causing hard-to-control high blood pressu…

This study is testing if using a patient's 'renin' hormone level can help doctors find the best dose of a lifelong medication for primary aldosteronism, a condition that causes high blood pressure. Researchers will compare this new approach to the standard way of adjusting the me…

This study is testing whether a minimally invasive heat treatment (thermal ablation) works as well as surgery to cure a specific hormone disorder that causes severe high blood pressure. Researchers will compare the two procedures in 122 patients who have the condition in one adre…

This study is testing a new blood test to more accurately find a specific, treatable cause of high blood pressure called primary aldosteronism. Researchers want to see if this new test works well even while people stay on their regular blood pressure pills, avoiding the need to s…

This study aims to improve the screening test for a specific hormonal cause of high blood pressure, called primary aldosteronism. It will test if taking a single dose of a steroid pill (dexamethasone) the night before a blood test makes the results clearer for patients who are al…

This study is comparing three different ways of performing a diagnostic test called adrenal venous sampling (AVS) for people with primary aldosteronism, a condition where the adrenal glands produce too much of a hormone that causes high blood pressure. The goal is to see which te…

This study aims to see if a new type of PET/CT scan is as good as the current standard test at figuring out which adrenal gland is causing problems in patients with high blood pressure and hormone issues. About 178 adults with adrenal nodules will get both tests in a random order…

This study aims to understand if people with a hormone condition called primary aldosteronism are more likely to develop memory problems or dementia. Researchers will follow 1,000 patients for up to 5 years, giving them regular memory tests and health check-ups. The goal is to le…

This study aims to find better ways to detect primary aldosteronism, a common but often missed cause of high blood pressure. Researchers will collect blood, urine, and tissue samples from 400 people with this condition, regular high blood pressure, or healthy controls. By analyzi…

This study follows 5,000 patients with primary aldosteronism, a hormonal cause of high blood pressure, for five years to understand how different treatments work. Researchers will track heart health, kidney function, and blood pressure control to identify which treatments lead to…