Primary aldosteronism
Clinical trials for Primary aldosteronism explained in plain language.
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Can a pill quiet the adrenal Glands' hormone overdrive?
Disease control Not yet recruitingThis trial asks whether baxdrostat, a daily pill that blocks an enzyme involved in aldosterone production, can reduce the overactive hormone-making spots in the adrenal glands of people with primary aldosteronism. Researchers will use specialized PET-CT scans to measure changes i…
Matched conditions: PRIMARY ALDOSTERONISM
Sponsor: Queen Mary University of London • Aim: Disease control
Last updated Sep 04, 2026 00:00 UTC
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Alcohol injection into adrenal tumors may offer surgery-free blood pressure control
Disease control Not yet recruitingThis study tests a procedure that uses a thin needle guided by an endoscope to inject alcohol into a benign adrenal tumor that produces too much aldosterone, a hormone that raises blood pressure. The goal is to destroy the tumor without surgery. The trial enrolls 30 adults with l…
Matched conditions: PRIMARY ALDOSTERONISM
Sponsor: Chongqing Medical University • Aim: Disease control
Last updated Jul 16, 2026 00:00 UTC
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Tighter blood pressure target may slash heart risks in hormone disorder
Disease control Not yet recruitingThis trial compares two blood pressure targets in people with primary aldosteronism, a hormonal condition that causes high blood pressure. One group aims for a systolic pressure below 120 mmHg (intensive), the other between 120 and 140 mmHg (standard). Over 6 to 10 years, researc…
Matched conditions: PRIMARY ALDOSTERONISM
Sponsor: Chongqing Medical University • Aim: Disease control
Last updated Jul 01, 2026 00:00 UTC
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New drug SAL0140 aims to tame Hormone-Driven high blood pressure
Disease control Not yet recruitingThis phase 2 trial tests a new drug called SAL0140 in 50 adults with primary aldosteronism, a condition where the adrenal glands make too much aldosterone, causing high blood pressure. Participants will receive either SAL0140 or a placebo for 12 weeks to see if it safely lowers b…
Matched conditions: PRIMARY ALDOSTERONISM
Phase 2 • Sponsor: Shenzhen Salubris Pharmaceuticals Co., Ltd. • Aim: Disease control
Last updated Jun 27, 2026 13:07 UTC
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New pill could tame Hormone-Driven high blood pressure
Disease control Not yet recruitingThis study tests an experimental drug called QLS1410 for people with primary aldosteronism, a condition where the adrenal glands make too much aldosterone, causing high blood pressure. The trial will compare the drug to a placebo in 60 adults to see if it safely lowers blood pres…
Matched conditions: PRIMARY ALDOSTERONISM
Phase 2 • Sponsor: Qilu Pharmaceutical Co., Ltd. • Aim: Disease control
Last updated Jun 27, 2026 12:23 UTC
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Radioactive tracer scan could replace invasive test for Hormone-Driven high blood pressure
Diagnosis Not yet recruitingResearchers compare two ways to find which adrenal gland overproduces aldosterone in people with primary aldosteronism. One method uses a metomidate PET-CT scan with a radioactive tracer; the other uses adrenal vein sampling, an invasive catheter procedure. The trial measures how…
Matched conditions: PRIMARY ALDOSTERONISM
Sponsor: Chinese University of Hong Kong • Aim: Diagnosis
Last updated Sep 13, 2026 00:00 UTC
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Sauna bathing may offer a sweat-based path to lower blood pressure
Symptom relief Not yet recruitingThis pilot study tests whether adding regular sauna sessions to usual care can help lower blood pressure in people with primary aldosteronism, a condition that causes high blood pressure. Ten adults will attend three 30-minute sauna sessions per week for two weeks while wearing a…
Matched conditions: PRIMARY ALDOSTERONISM
Sponsor: University of Calgary • Aim: Symptom relief
Last updated Sep 02, 2026 00:00 UTC
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Virtual doppelgänger may help pick right patients for kidney nerve treatment
Knowledge-focused Not yet recruitingThis pilot study will test whether a personalized computer model, called a 'digital twin,' can predict which patients with high blood pressure will respond to a procedure called renal denervation. The study will enroll 60 people, including those with resistant hypertension, untre…
Matched conditions: PRIMARY ALDOSTERONISM
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:00 UTC