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Massive study aims to refine testing for Hormone-Driven hypertension

NCT ID NCT07252284

Knowledge-focused Sponsor: Chinese Academy of Medical Sciences, Fuwai Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at a special blood test called adrenal venous sampling (AVS) used in people with primary aldosteronism, a condition where the adrenal glands make too much of a hormone that raises blood pressure. The goal is to see how well AVS helps doctors choose the right treatment and whether that leads to fewer heart problems. About 5,000 participants will be followed for one year to track outcomes like stroke and heart failure.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 5,000 people

The number the study aims to enrol. It can still change while the study runs.

Started

May 2025

Expected to finish

Aug 2029

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

All patients with confirmed primary aldosteronism underwent adrenal venous sampling.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Patients with confirmed primary aldosteronism; 2. Patients undergoing adrenal venous sampling for subtype classification of primary aldosteronism. Exclusion Criteria: 1. Severe comorbidity, including stroke, myocardial infarction, heart failure, severe valvular heart disease, liver cirrhosis, and metastatic tumor within the previous 3 months； 2. An estimated glomerular filtration rate \<45 ml/min/1.73 m2, or serum creatinine \>176 μmol/L； 3. Patients who refuse adrenalectomy; 4. Suspected of having an adrenocortical carcinoma; 5. Allergy to contrast agent; 6. Pregnant, nursing, or planning to become pregnant

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Conditions

The condition(s) this trial relates to.

hyperaldosteronism primary aldosteronism

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Adrenal venous sampling Adrenalectomy Hyperaldosteronism

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The study's own enquiry address

    This study publishes an address for enquiries. See it below .

  2. The places running it

    76 sites. The list below names each one and where it is.

  3. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  4. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Affilated Zhongshan Hospital of Dalian University

    RECRUITING

    Dalian, Liaoning, 116001, China

  • Beijing Luhe Hospital, Capital Medical University

    RECRUITING

    Beijing, Beijing Municipality, 101100, China

  • Cardiovascular Hospital Xiamen University

    RECRUITING

    Xiamen, Fujian, 361016, China

  • Central Hospital Affiliated to Shandong First Medical University

    RECRUITING

    Jinan, Shandong, 250013, China

  • Changdu People's Hospital of Tibet

    RECRUITING

    Chamdo, Tibet, 854000, China

  • Chengdu Fifth People's Hospital

    RECRUITING

    Chengdu, Sichuan, 611130, China

  • China-Japan Friendship Hospital

    RECRUITING

    Beijing, Beijing Municipality, 100029, China

  • Chongqing General Hospital

    RECRUITING

    Chongqing, Chongqing Municipality, 401147, China

  • Chongqing University Central Hospital

    RECRUITING

    Chongqing, Chongqing Municipality, 400000, China

  • Chuiyangliu Hospital affiliated to Tsinghua University

    RECRUITING

    Beijing, Beijing Municipality, 100022, China

  • First Affiliated Hospital, Fujian Medical University, Fuzhou, China,

    RECRUITING

    Fuzhou, Fujian, 0591-87982222, China

  • Frist Aiffiliated Hospital of Dalian Medical University

    RECRUITING

    Dalian, Liaoning, 116011, China

  • Fuwai Central China Cardiovascular Hospital

    RECRUITING

    Zhengzhou, Henan, 450000, China

  • Fuwai Hospital Chinese Academy of Medical Sciences, Shenzhen

    RECRUITING

    Shenzhen, Guangdong, 518000, China

  • Fuwai Hospital, National Center for Cardiovascular Disease, Chinese Academy of Medical Sciences and Peking Union Medical College

    RECRUITING

    Beijing, Beijing Municipality, 100037, China

  • Fuwai Yunnan Cardiovascular Hospital

    RECRUITING

    Kunming, Yunnan, 650102, China

  • Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences)

    RECRUITING

    Guangzhou, Guangdong, 510080, China

  • Guizhou Provincial People's Hospital, Guiyang, Guizhou 550002, China.

    RECRUITING

    Guiyang, Guizhou, 550002, China

  • Hainan General Hospital, Department of Cardiology

    RECRUITING

    Hainan, Hainan, 570311, China

  • Hainan General Hospital, Department of Endocrinology

    RECRUITING

    Haikou, Hainan, 570311, China

  • Henan Provincial People's Hospital

    RECRUITING

    Zhengzhou, Henan, 450003, China

  • Inner Mongolia Xing'an League People's Hospital

    RECRUITING

    Ulanhot, Neimenggu, 137400, China

  • Jiangxi Provincial People's Hospital (The First Affiliated Hospital of Nanchang Medical College)

    RECRUITING

    Nanchang, Jiangxi, 330038, China

  • Jilin Province FAW General Hospital

    RECRUITING

    Changchun, Jilin, 130051, China

  • Kai Feng the Peoples Hospital

    RECRUITING

    Kaifeng, Henan, 475002, China

  • Lanzhou University Second Hospital

    RECRUITING

    Lanzhou, Gansu, 730000, China

  • Nanning Third People's Hospital

    RECRUITING

    Nanning, Guangxi, 547000, China

  • Peking University First Hospital

    RECRUITING

    Beijing, Beijing Municipality, 100034, China

  • Peking University People's Hospital

    RECRUITING

    Beijing, Beijing Municipality, 100044, China

    Contact Email: •••••@•••••

  • People's Hospital Affiliated to ChongqingThree Gorges Medical college

    RECRUITING

    Chongqing, Chongqing Municipality, 404100, China

  • People's Hospital of Donga County, Shandong Province

    RECRUITING

    Liaocheng, Shandong, 252200, China

  • Qilu Hospital of Shandong University

    RECRUITING

    Jinan, Shandong, 250012, China

  • Qingdao Hospital University of Health and Rehabilitation Sciences (Qingdao Municipal Hospital)

    RECRUITING

    Qingdao, Shandong, 266000, China

  • Qinghai Province Cardiovascular and Cerebrovascular Disease Specialist Hospital

    RECRUITING

    Xining, Qinghai, 810000, China

  • Qinghai University Affiliated Hospital

    RECRUITING

    Xining, Qinghai, 810001, China

  • Renmin Hospital of Wuhan University

    RECRUITING

    Wuhan, Hubei, 430060, China

  • Second Affiliated Hospital of Nanchang University

    RECRUITING

    Nanchang, Jiangxi, 330006, China

  • Shanghai General Hospital ( originally named Shanghai First People's Hospital), Shanghai Jiao Tong University School of Medicine

    RECRUITING

    Shanghai, Shanghai Municipality, 200080, China

  • Shanghai Institute of Hypertension, Ruijin Hospital, Shanghai Jiaotong University School of Medicine

    RECRUITING

    Shanghai, Shanghai Municipality, 200025, China

  • Shanghai Putuo District Central Hospital

    RECRUITING

    Shanghai, Shanghai Municipality, 200062, China

  • Shenzhen Dapeng New District Kuiyong People's Hospital

    RECRUITING

    Shenzhen, Guangdong, 518116, China

  • Shenzhen Third People's Hospital，Shenzhen, Guangdong Province 518112, China

    RECRUITING

    Shenzhen, Guangdong, 518112, China

  • TEDA International Cardiovascular Hospital

    RECRUITING

    Tianjin, Tianjin Municipality, 300457, China

  • Tangshan hongci Hospital

    RECRUITING

    Tangshan, Hebei, 063000, China

  • The Affiliated Hospital of Guizhou Medical University

    RECRUITING

    Guiyang, Guizhou, 550004, China

  • The Affiliated Hospital of Southwest Jiaotong University, The Third People's Hospital of Chengdu, Chengdu, China

    RECRUITING

    Chengdu, Sichuan, 610031, China

  • The First Affiliated Hospital of Chengdu Medical College

    RECRUITING

    Chengdu, Sichuan, 610500, China

  • The First Affiliated Hospital of Gannan Medical University

    RECRUITING

    Ganzhou, Jiangxi, 341000, China

  • The First Affiliated Hospital of Guangxi Medical University

    RECRUITING

    Nanning, Guangxi, 530000, China

  • The First Affiliated Hospital of Harbin Medical University

    RECRUITING

    Harbin, Heilongjiang, 150001, China

  • The First Affiliated Hospital of Kunming Medical University

    RECRUITING

    Kunming, Yunnan, 650031, China

  • The First Affiliated Hospital of Zhengzhou University

    RECRUITING

    Zhengzhou, Henan, 450052, China

  • The First Hospital of Jilin University

    RECRUITING

    Changchun, Jilin, 130021, China

  • The First People's Hospital of Yinchuan

    RECRUITING

    Yinchuan, Ningxia, 750000, China

  • The Forth People's Hosptal of Nanhai District of Foshan City

    RECRUITING

    Foshan, Guangdong, 528211, China

  • The Second Affiliated Hospital Of Guizhou Medical University

    RECRUITING

    Kaili, Guizhou, 556000, China

  • The Second Affiliated Hospital of Harbin Medical University

    RECRUITING

    Harbin, Heilongjiang, 150086, China

  • The Second Affliated Hospital Of GuangXi Medical Univesity

    RECRUITING

    Nanning, Guangxi, 530007, China

  • The Second Hospital of Tianjin Medical University

    RECRUITING

    Tianjin, Tianjin Municipality, 300211, China

  • The first affiliated hospital of USTC

    RECRUITING

    Hefei, Anhui, 230036, China

  • The second hospital of Dalian Medical University

    RECRUITING

    Dalian, Liaoning, 116027, China

  • Tianjin Medical University General Hospital

    RECRUITING

    Tianjin, Tianjin Municipality, 300052, China

  • Xi'an People's Hospital

    RECRUITING

    Xi’an, Shanxi, 710018, China

  • Xiangyang Central Hospital, Affiliated Hospital of Hubei University of Arts and Science

    RECRUITING

    Xiangyang, Hubei, 441021, China

  • Xinjiang Uygur Autonomous Region People's Hospital

    RECRUITING

    Ürümqi, Xinjiang, 830001, China

  • Xuzhou Central Hospital, Jiangsu

    RECRUITING

    Xuzhou, Jiangsu, 221009, China

  • Yan'an Affiliated Hospital of Kunming Medical University

    RECRUITING

    Kunming, Yunnan, 650051, China

  • Yichang Central People's Hospital

    RECRUITING

    Yichang, Hubei, 43000, China

  • Yili Kazak Autonomous Prefecture Friendship Hospital

    RECRUITING

    Yining, Xinjiang, 835000, China

  • Zhejiang Hospital

    RECRUITING

    Hangzhou, Zhejiang, 310000, China

  • Zhengzhou Central Hospital Affiliated to Zhengzhou University

    RECRUITING

    Zhengzhou, Henan, 450007, China

  • Zhengzhou Yihe Hospital

    RECRUITING

    Zhengzhou, Henan, 450018, China

  • Zhoukou Central Hospital

    RECRUITING

    Zhoukou, Henan, 466000, China

  • Zhuzhou Hospital Affiliated to Xiangya School of Medicine,Central South University

    RECRUITING

    Zhuzhou, Hunan, 412000, China

  • the Second Hospital, Cheeloo College of Medicine, Shandong University

    RECRUITING

    Jinan, Shandong, 250000, China

  • the second hospital of ShanXi medical unversity

    RECRUITING

    Taiyuan, Shanxi, 030001, China

More trials for these conditions

Other studies related to the condition(s) this trial covers.