Massive study aims to uncover hidden cause of high blood pressure
NCT ID NCT07378176
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study follows 5,000 people with primary aldosteronism, a common but often missed cause of high blood pressure that raises heart and kidney risks. Researchers will track treatments like medication, surgery, and other procedures over five years to see which works best. The goal is to provide real-world evidence to improve diagnosis and long-term care.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this study could provide better guidelines for diagnosing and treating primary aldosteronism, potentially reducing heart and kidney complications.
- What could go wrong
- This is an observational study, not a treatment trial. It will not directly test a new therapy, and results may take years to influence practice.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 5,000 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jan 2026
- Expected to finish
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Dec 2031
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Patients with a diagnosis of primary aldosteronism (PA) confirmed in accordance with current clinical guidelines.
- Ages
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18 to 80 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Aged between 18 and 80 years old. 2. Biochemically confirmed diagnosis of Primary Aldosteronism (PA) according to contemporary guidelines (e.g., confirmed positive case detection test and confirmatory test). 3. Voluntary to sign the informed consent. Exclusion Criteria: 1. patients with severe cardiac, hepatic or renal dysfunction; 2. Diagnosis of secondary hypertension other than PA.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
2 sites. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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The First Affiliated Hospital of Chengdu Medical College
RECRUITINGChengdu, Sichuan, 610000, China
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The First Affiliated Hospital of Xinjiang Medical University
RECRUITINGÜrümqi, Xinjiang, 830000, China
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