POSTURAL TACHYCARDIA SYNDROME
Clinical trials for POSTURAL TACHYCARDIA SYNDROME explained in plain language.
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POTS patients may find relief from standing symptoms with moxonidine
Symptom relief OngoingThis study looks at whether moxonidine, a drug that lowers sympathetic nerve activity, can reduce symptoms like rapid heartbeat and lightheadedness in people with Postural Tachycardia Syndrome (POTS). About 48 women with POTS will take either moxonidine or a placebo for 4 weeks. …
Matched conditions: POSTURAL TACHYCARDIA SYNDROME
Phase: EARLY_PHASE1 • Sponsor: Vanderbilt University Medical Center • Aim: Symptom relief
Last updated May 26, 2026 04:24 UTC
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Could a simple breathing trick ease POTS symptoms?
Symptom relief OngoingThis study tests whether breathing through a small resistance device can help people with Postural Orthostatic Tachycardia Syndrome (POTS) stand up longer and feel better. POTS causes a rapid heart rate and symptoms like dizziness when standing. The study involves 30 adults diagn…
Matched conditions: POSTURAL TACHYCARDIA SYNDROME
Phase: NA • Sponsor: Alfredo Gamboa • Aim: Symptom relief
Last updated May 26, 2026 03:57 UTC
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Saltwater IV may boost exercise in POTS patients
Symptom relief OngoingThis study looks at whether a simple saltwater infusion can help people with Postural Tachycardia Syndrome (POTS) exercise more easily. Forty adults with POTS will have their exercise ability tested after receiving either saline or a placebo. The goal is to see if the saline impr…
Matched conditions: POSTURAL TACHYCARDIA SYNDROME
Phase: NA • Sponsor: Vanderbilt University Medical Center • Aim: Symptom relief
Last updated May 18, 2026 12:07 UTC
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Salt study seeks clues to POTS mystery
Knowledge-focused OngoingThis study looks at how the body handles salt and a hormone called aldosterone in people with Postural Tachycardia Syndrome (POTS). Researchers want to see if a high-salt diet can improve symptoms and blood volume. The study involves both POTS patients and healthy volunteers to c…
Matched conditions: POSTURAL TACHYCARDIA SYNDROME
Phase: NA • Sponsor: Vanderbilt University • Aim: Knowledge-focused
Last updated May 26, 2026 04:19 UTC
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Could POTS be an autoimmune disease? new study investigates
Knowledge-focused OngoingThis study looks at whether postural tachycardia syndrome (POTS) is caused by an autoimmune reaction. Researchers will test if stimulating the vagus nerve can reduce symptoms and inflammation. The study involves 80 people, including those with POTS and healthy volunteers.
Matched conditions: POSTURAL TACHYCARDIA SYNDROME
Phase: NA • Sponsor: University of Oklahoma • Aim: Knowledge-focused
Last updated May 26, 2026 04:15 UTC
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Blood test may unlock secrets of POTS
Knowledge-focused OngoingThis study looks at whether a simple blood test can measure how well the body clears a stress chemical called norepinephrine in people with Postural Tachycardia Syndrome (POTS). POTS causes a rapid heart rate and dizziness when standing. The researchers will compare blood and uri…
Matched conditions: POSTURAL TACHYCARDIA SYNDROME
Sponsor: Vanderbilt University Medical Center • Aim: Knowledge-focused
Last updated May 26, 2026 03:58 UTC
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POTS brain fog mystery under the microscope
Knowledge-focused OngoingThis study looks at why people with Postural Tachycardia Syndrome (POTS) often have trouble thinking clearly, known as 'brain fog.' Researchers will compare brain scans of 21 adults with and without POTS while they do mental tasks, both sitting and standing. The goal is to see if…
Matched conditions: POSTURAL TACHYCARDIA SYNDROME
Phase: NA • Sponsor: Milton S. Hershey Medical Center • Aim: Knowledge-focused
Last updated May 26, 2026 03:55 UTC
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Salt mystery: why POTS patients may not hold onto sodium
Knowledge-focused OngoingThis study looks at whether people with Postural Orthostatic Tachycardia Syndrome (POTS) have trouble holding onto salt in their urine compared to healthy people. Researchers will measure salt and stress hormone levels after a salt load. The goal is to better understand the body'…
Matched conditions: POSTURAL TACHYCARDIA SYNDROME
Phase: NA • Sponsor: Vanderbilt University • Aim: Knowledge-focused
Last updated May 22, 2026 13:55 UTC
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Can a wakefulness drug clear the fog for POTS patients?
Knowledge-focused OngoingThis study looks at whether a single dose of modafinil, a drug that promotes wakefulness, can improve concentration and mental clarity in people with Postural Tachycardia Syndrome (POTS). Twenty adults diagnosed with POTS will take the drug and then complete computer-based tests …
Matched conditions: POSTURAL TACHYCARDIA SYNDROME
Phase: EARLY_PHASE1 • Sponsor: Vanderbilt University Medical Center • Aim: Knowledge-focused
Last updated May 22, 2026 13:51 UTC
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POTS study tests drug to uncover root cause of racing heart
Knowledge-focused OngoingThis study looks at why people with Postural Tachycardia Syndrome (POTS) get a fast heart rate and feel dizzy when standing. Researchers will give a blood pressure drug called moxonidine to 48 adults with POTS to see if lowering nerve activity eases symptoms. The goal is not to c…
Matched conditions: POSTURAL TACHYCARDIA SYNDROME
Phase: EARLY_PHASE1 • Sponsor: Vanderbilt University Medical Center • Aim: Knowledge-focused
Last updated May 20, 2026 11:57 UTC
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POTS puzzle: is it an autoimmune attack?
Knowledge-focused ENROLLING_BY_INVITATIONThis study looks at whether people with POTS (a condition causing a rapid heart rate upon standing) have higher levels of certain immune proteins that might attack their own nervous system. Researchers will measure these proteins in blood samples from 58 participants, including b…
Matched conditions: POSTURAL TACHYCARDIA SYNDROME
Phase: NA • Sponsor: Vanderbilt University Medical Center • Aim: Knowledge-focused
Last updated May 18, 2026 12:14 UTC
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Can a watch reveal hidden sleep struggles in Standing-Intolerant patients?
Knowledge-focused OngoingThis study uses activity watches (actigraphy) to measure sleep disturbances in people with orthostatic intolerance, a condition where standing causes dizziness or fainting. Researchers will compare sleep quality between 100 patients and healthy volunteers. The goal is to understa…
Matched conditions: POSTURAL TACHYCARDIA SYNDROME
Sponsor: Satish R. Raj • Aim: Knowledge-focused
Last updated May 18, 2026 12:03 UTC