Can a watch reveal hidden sleep troubles in POTS patients?
NCT ID NCT00692471
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study uses a wrist-worn activity watch to measure sleep quality in people with orthostatic intolerance (a condition where standing causes dizziness) compared to healthy volunteers. Researchers want to see if these patients have worse sleep, like taking longer to fall asleep. The study involves 100 adults aged 18-65 and is purely observational, aiming to gather knowledge rather than test a treatment.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this study could help doctors better understand and diagnose sleep issues in people with orthostatic intolerance.
- What could go wrong
- This is a small, early-stage observational study. It only measures sleep, not treatments, so it may not lead to direct improvements for patients.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 100 people
The number the study aims to enrol. It can still change while the study runs.
- Start date
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Jun 2008
- Expected to finish
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Dec 2029
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Patients diagnosed with the Postural Tachycardia Syndrome. The criteria include: * an increase in heart rate on standing (from supine) of \>30 bpm * in the setting of symptoms of cerebral hypoperfusion that are worse with standing and better when recumbent * the symptoms are daily or almost daily * the symptoms are chronic (lasting greater than 6 motnsh)
- Ages
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18 to 65 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Diagnosed with orthostatic intolerance by the Vanderbilt Autonomic Dysfunction Center * Control subjects will be free of orthostatic intolerance and other major medical problems, free of medications during the study * Age between 18-65 years * Male and female subjects are eligible. * Able and willing to provide informed consent Exclusion Criteria: * Overt cause for postural tachycardia (such as acute dehydration) * Self-report of pregnancy * Inability to give, or withdrawal of, informed consent * Other factors which in the investigator's opinion would prevent the subject from completing the protocol
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Vanderbilt University
Nashville, Tennessee, 37232-2195, United States
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