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Could a blood pressure pill calm racing hearts in POTS?

NCT ID NCT04140721

First seen Mar 31, 2026 · Last updated Jun 18, 2026 · Updated 10 times

Summary

This study tests whether moxonidine, a blood pressure medication that lowers sympathetic nerve activity, can reduce symptoms like rapid heartbeat and lightheadedness in people with Postural Tachycardia Syndrome (POTS). About 48 participants will take either moxonidine or a placebo for 4 weeks to compare changes in symptom burden and heart rate when standing. The goal is to find more personalized treatments for this condition that mainly affects young women.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Vanderbilt University Medical Center

    Nashville, Tennessee, 37221, United States

Conditions

The condition(s) this trial relates to.

postural orthostatic tachycardia syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.