POSTPARTUM DEPRESSION

This study tests whether spending more than 2 days in a kangaroo mother care (KMC) ward—where mothers hold their low-birthweight babies skin-to-skin and get breastfeeding support—can lower the risk of postpartum depression. About 1,900 mothers and their preterm infants in Zambia …

This study tests a new program called MOMI PODS that provides extra medical and emotional support to new mothers who had pregnancy complications like high blood pressure, diabetes, or depression. About 384 mother-baby pairs will be randomly assigned to either the new program or s…

This study looks at whether the ROSE program, which has been shown to prevent about half of postpartum depression cases in women at higher risk, can work for all new mothers. Researchers will enroll 2,320 pregnant women from a large health system in Detroit to see if offering the…

This study tests whether a virtual group program called Mothers and Babies can prevent postpartum depression in immigrant Latinas who are at risk. About 300 pregnant women and new mothers will either join the program via Zoom or receive usual support services. Researchers will tr…

This study tests a new type of talk therapy called Engage & Connect for mothers with postpartum depression. The therapy focuses on helping moms plan and do rewarding social activities to reduce feelings of isolation. Sixty participants will receive either this new therapy or a st…

This study tests a group-based mindfulness program called 'Mindful with your Baby' for mothers with babies 5-9 months old who feel depressed, anxious, or stressed. The program includes the baby in sessions to improve bonding. Researchers will measure changes in mood, stress, and …

This study tests whether extra support from a doula—both in the hospital and after going home—can help mothers of very premature babies feel less stressed, depressed, or anxious. About 20 mothers will be randomly assigned to receive this support or standard care. The goal is to s…

This observational study follows 200 people with postpartum depression who are starting zuranolone (Zurzuvae). Participants complete online surveys about their symptoms at 15, 45, and 90 days after their first dose. The goal is to see how symptoms change over time in real-world u…

This study looks at how poor sleep during pregnancy can lead to stress and mental health issues like depression and anxiety after giving birth. Researchers will follow 114 pregnant women and test an online sleep therapy program to see if it helps prevent these problems. The goal …

This study follows 600 pregnant women with gestational diabetes to see how depression and diabetes affect each other during pregnancy and after birth. Some participants will receive short health education videos about diet, exercise, and support. The goal is to understand the con…

This study looks at whether doulas with extra training in mental health support can help pregnant women in rural Montana feel more confident and less depressed. About 75 pregnant women will be split into three groups: one with a specially trained doula, one with a regular doula, …