Can a simple program slash postpartum depression for every mom?
NCT ID NCT05700760
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at whether the ROSE program, which has been shown to prevent about half of postpartum depression cases in women at higher risk, can work for all new mothers. Researchers will enroll 2,320 pregnant women from a large health system in Detroit to see if offering the program to everyone is effective, cost-saving, and fair. The goal is to help decide if ROSE should be a standard part of care for all pregnant women.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 2,320 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jun 2023
- Expected to finish
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Dec 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Female participants only
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Is aged 18 or older 2. Is receiving prenatal services within the U.S 3. Is between 12-32 weeks pregnant 4. Speaks and understand English well enough to understand questionnaires when they are read aloud 5. Has access to a telephone through owning one, a relative/friend, or an agency 6. Is willing and able to provide the name and contact information of at least two locator persons Exclusion Criteria: 1. Has a current major depressive episode 2. Has current or past diagnosis of a bipolar disorder or a psychotic disorder
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Michigan State University
RECRUITINGFlint, Michigan, 48502, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- A 12-minute video could save new mothers' lives – can it teach them to spot danger?
- Can a phone app shield new mothers from postpartum depression?
- A single day of online therapy could curb postpartum depression
- Online exercise program aims to revive postpartum sexual health
- A headset for depression in pregnancy — science tests a Drug-Free option