PNEUMONIA

This study tests whether a ketogenic (low-carb, high-fat) diet helps older adults (55+) with pneumonia maintain muscle function better than a standard hospital diet. Thirty participants will be randomly assigned to one of the two diets during their hospital stay. The main goals a…

This early-phase trial tests whether a traditional Chinese herbal formula combined with bacteriophages (viruses that kill bacteria) can clear drug-resistant bacteria in 240 adults with severe pneumonia. The goal is to improve recovery and lower death rates. Participants must have…

This study tests whether a pharmacist-led electronic consultation can help people with HIV use their medications more safely and improve lung health. About 480 participants who smoke or take certain lung or stomach medications will receive tailored recommendations from pharmacist…

This study looks at whether using lower doses of two blood thinners (argatroban and enoxaparin) can reduce bleeding and clotting problems in adults on ECMO, a machine that helps the heart and lungs. About 200 participants with pneumonia or heart failure will be enrolled. The goal…

This study tests a new AI system that helps doctors perform bronchoscopy—a procedure where a thin tube is inserted into the lungs—for patients with severe pneumonia. The AI provides real-time visual and voice guidance to locate the right lung areas and describe findings, but doct…

This study aims to improve how doctors identify the exact germ causing severe pneumonia in children. It will include 50 children in intensive care who are on breathing tubes. Researchers will collect extra samples of lung fluid and blood to test the body's response to the infecti…

This study looks at whether a simple urine test can accurately diagnose pneumococcal pneumonia in children under five in Malawi, where the disease is a leading cause of death. Researchers will test 350 stored urine samples from healthy kids and those with pneumonia, comparing res…

This study tests whether using a high-flow nasal cannula (a device that delivers warm, moist oxygen) for 24 hours right after major abdominal surgery can prevent serious lung complications like pneumonia or collapsed lungs. About 580 adults having long abdominal surgeries will be…

This study tests four different nebulized solutions (salt water at various strengths and distilled water) to see which one best helps pneumonia patients clear mucus from their lungs. Eighty adults with pneumonia who need help coughing up phlegm will receive treatment four times d…

This study tests whether a simple breathing exercise called pursed-lip breathing can help children aged 3-4 with pneumonia. The exercise involves breathing in through the nose and out through pursed lips, done twice daily for three days. Researchers will measure changes in breath…

This study tests whether adding probiotic nasal spray and oral probiotics to standard pneumonia treatment helps children aged 6 to 36 months recover faster. About 330 hospitalized children will be split into three groups: one gets a placebo, one gets a probiotic nasal spray, and …

This study tests whether a high-flow nasal cannula (a device that delivers warm, humidified oxygen) can prevent dangerously low oxygen levels in children aged 1 to 6 years during a sedated bronchoscopy (a procedure to look inside the lungs). About 430 children will be randomly as…

This study looks at two ways to give sedation medicine to children aged 5-10 who are on breathing machines for pneumonia. One method gives medicine continuously, the other pauses it daily. The goal is to see which approach keeps children more comfortable and safe. About 96 childr…

This study tests a chatbot called 'Pneumonia Care Helper' to see if it helps caregivers of elderly pneumonia patients learn more than traditional paper handouts. About 150 caregivers will use either the chatbot or paper instructions for 5 days. The goal is to see if the chatbot i…

This study will follow 2,000 people—children under 5 and adults aged 16-60—in 30 villages in rural India to track how often they get serious lung infections like RSV, flu, and COVID-19. Researchers will visit homes weekly and test samples to measure how many people get sick, need…

This study looks at 150 ICU patients with pneumonia who need a breathing machine. Doctors will use bedside ultrasound to measure how well their breathing muscles work during the process of taking them off the machine. The goal is to find simple ways to predict who might have trou…

This study will review the medical records of 500 adults hospitalized with pneumonia between 2023 and 2026. Researchers aim to identify factors like age, other illnesses, and lab results that affect patient recovery and survival. The goal is to use this information to help doctor…

This study will follow about 2,700 adults with pneumonia to track their recovery and identify who is at risk for severe illness. Researchers will collect health data and samples to understand why some people get worse. The goal is to improve how doctors predict and manage pneumon…

This study looks at whether patients who get a breathing tube in an emergency are more likely to develop pneumonia than those who get one in a planned, non-emergency setting. Researchers will review medical records from 600 adults treated in 2024. The goal is to understand how ur…

This study looks at how different levels of pressure from a breathing machine (ventilator) affect the lungs and diaphragm in 25 ICU patients with respiratory failure. Each patient will try three pressure settings to see which one helps them breathe more efficiently and with less …

This study will observe 4,000 children under 5 who test positive for RSV and visit pediatric emergency rooms in Turkey. Researchers want to learn how many need hospital care, breathing support, or ICU admission. The goal is to better understand the virus's impact and help hospita…