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Can a simple ultrasound predict breathing machine success in ICU pneumonia patients?

NCT ID NCT07405567

Knowledge-focused Sponsor: Bursa Sevket Yilmaz Training and Research Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study will use bedside ultrasound to look at the diaphragm and other breathing muscles in 150 ICU patients with pneumonia who are on a breathing machine. The goal is to see if muscle measurements can help predict whether a patient will successfully come off the machine or fail. No new treatment is being tested; researchers are just observing and collecting data to better understand weaning difficulties.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this study could help doctors identify which ICU patients with pneumonia are at risk of failing to come off a breathing machine, potentially leading to better monitoring and earlier interventions.
What could go wrong
This is an early observational study at a single center, not a treatment trial. The findings may not apply to all patients or change current care practices.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 150 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Feb 2026

An estimate. Start dates often move.

Expected to finish

Feb 2027

An estimate. End dates often move.

Lead sponsor

A government agency

The lead sponsor is a government body.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

The study population consists of adult patients aged 18 years and older who are admitted to the intensive care unit with pneumonia and require invasive mechanical ventilation via endotracheal intubation. Patients are followed prospectively during the weaning process from mechanical ventilation and undergo serial bedside ultrasonographic assessment of respiratory muscles as part of observational data collection. All patients receive standard intensive care management as determined by the treating clinical team.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age ≥ 18 years * Admission to the intensive care unit with a diagnosis of pneumonia * Receiving invasive mechanical ventilation via endotracheal intubation * Expected to undergo a weaning process from mechanical ventilation * Written informed consent obtained from the patient or legally authorized representative Exclusion Criteria: * Known neuromuscular disease affecting respiratory muscles * High cervical spinal cord injury * History of major neck, thoracic, or diaphragmatic surgery * Acute thoracic trauma or pneumothorax * Central nervous system pathology affecting respiratory drive * Continuous neuromuscular blocking agent use * Pregnancy

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Conditions

The condition(s) this trial relates to.

pneumonia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Invasive mechanical ventilation Pneumonia Respiratory muscle dysfunction Weaning from mechanical ventilation in care unit

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Principal Investigator

    Bursa, Turkey (Türkiye)

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