PERIMENOPAUSE
Clinical trials for PERIMENOPAUSE explained in plain language.
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Natural steroid shows promise for menopausal depression in small trial
Symptom relief CompletedThis study tested whether a natural brain steroid called pregnenolone could reduce depression symptoms in women going through menopause or perimenopause. 73 women aged 40-67 took either pregnenolone or a placebo for a set period. The main goal was to see if the treatment led to a…
Matched conditions: PERIMENOPAUSE
Phase: PHASE1, PHASE2 • Sponsor: University of Texas Southwestern Medical Center • Aim: Symptom relief
Last updated May 26, 2026 06:59 UTC
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Pump iron, boost brain: creatine and training target menopause symptoms
Symptom relief CompletedThis pilot study looked at whether high-intensity resistance training combined with creatine supplements can improve muscle quality, thinking skills, and menopause symptoms in perimenopausal women aged 38-60. Fifty-five healthy women were randomly assigned to take creatine, a pla…
Matched conditions: PERIMENOPAUSE
Phase: NA • Sponsor: University of North Carolina, Chapel Hill • Aim: Symptom relief
Last updated May 26, 2026 06:58 UTC
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Can plants ease menopause? 900 women test natural relief
Symptom relief CompletedThis study tested plant-based health products to see if they help with perimenopause symptoms like hot flashes, mood swings, and sleep problems. About 900 women aged 37-55 who were in perimenopause took either the plant product or a placebo. The goal was to measure changes in the…
Matched conditions: PERIMENOPAUSE
Phase: NA • Sponsor: Radicle Science • Aim: Symptom relief
Last updated May 19, 2026 11:59 UTC
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Creatine shows promise for menopause brain fog and fatigue
Symptom relief CompletedThis study looked at whether taking creatine supplements for 8 weeks can improve thinking, reduce fatigue, and support brain health in women going through menopause or perimenopause. 36 women took either creatine HCl, creatine ethyl ester, or a placebo. Researchers measured fatig…
Matched conditions: PERIMENOPAUSE
Phase: NA • Sponsor: University of Novi Sad, Faculty of Sport and Physical Education • Aim: Symptom relief
Last updated May 15, 2026 11:54 UTC