Parkinson disease (PD)

This trial tests three deep brain stimulation (DBS) settings in people with Parkinson's disease who already have a Boston Scientific Vercise system implanted. The settings are pure anodic, pure cathodic, and a mix of both. Researchers want to see which setting offers the best sym…

Researchers are exploring whether a wrist-worn device called the Beechband, which delivers intermittent vibrations, can change movement symptoms and everyday experiences for people with Parkinson's disease. About 60 participants will be randomly assigned to wear the device for ei…

This study looked at whether a special exercise program focusing on muscle power (moving quickly) could help people with Parkinson's disease who have slow movements (bradykinesia). Twenty-two adults with Parkinson's were split into two groups: one did standard exercises, and the …

This study tests whether mild electrical stimulation of the ear, combined with physical and speech therapy, can improve symptoms like voice problems, swallowing, and balance in people with Parkinson's disease. 46 participants will receive either active or sham stimulation during …

This study tests whether a 7-week ballroom dance program, called Parkinson Ballroom Fitness, can improve walking, balance, and quality of life in people with Parkinson's disease. About 50 participants will be randomly assigned to dance or usual care. The program uses waltz, swing…

This pilot study tests whether a Parkinson's-specific Tai Chi program can improve movement and non-movement symptoms like balance, fatigue, and mood. Thirty adults with mild to moderate Parkinson's will either take Tai Chi classes plus usual care or just usual care for 12 weeks. …

Researchers are sequencing the gut microbiomes of people with a wide range of conditions, from autism and Alzheimer's to Crohn's disease and multiple sclerosis, to see whether bacterial patterns differ by disease. The study also enrolls healthy participants for comparison. By mat…

This study looks at whether the Parkinson's drug Levodopa-Benserazide affects gum health and inflammation. Researchers will measure gum health and saliva markers in 136 people, including Parkinson's patients with and without gum disease, and healthy controls. The goal is to under…

This observational study follows 36 people with neurologic conditions like traumatic brain injury, cerebral palsy, multiple sclerosis, or Alzheimer's who are already receiving intranasal MuSE stem cell or exosome therapy as part of their routine care. Researchers track safety and…

This study looks at data from 1 million adults worldwide to see if eating nuts is linked to a lower risk of diseases like diabetes, heart disease, cancer, and dementia. Researchers will combine information from many past studies to get clearer answers. The goal is to understand i…