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Nuts vs. disease: Million-Person study seeks answers

NCT ID NCT07205978

Knowledge-focused Sponsor: Institut Investigacio Sanitaria Pere Virgili Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at data from 1 million adults worldwide to see if eating nuts is linked to a lower risk of diseases like diabetes, heart disease, cancer, and dementia. Researchers will combine information from many past studies to get clearer answers. The goal is to understand if nuts can help prevent these conditions, not to test a new treatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 1,000,000 people

The number the study aims to enrol. It can still change while the study runs.

Started

Oct 2025

Expected to finish

Jan 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Adult participants from Cohorts larger than 5000 participants and with at least a mean of 5 years of follow-up

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: Prospective studies with: * Dietary data (consumption of nuts, both overall and/or by type) from semiquantitative food frequency questionnaires * Available data on at least two of the health outcomes of interest * More than 1,000 adult participants (aged 18 and over) * A minimum of five years of median follow-up Exclusion Criteria: * Prospective studies determining the consumption of nuts in combination with other food groups (e.g., seeds) or with other nut forms (e.g., butter or oil) * Participants with: * Missing data on age, sex, and nut consumption. * Extreme energy intakes (\<600 or \>3,500 kcal for women and \<800 or \>4,200 kcal for men) * The disease of interest at baseline

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Conditions

The condition(s) this trial relates to.

Alzheimer disease Death diabetes mellitus neoplasm Parkinson disease cancer prevention target cardiovascular disorder prevention target dementia prevention target type 2 diabetes mellitus prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Cancer Cardio vascular disease Death Dementia Dementia Alzheimer type Diabetes (DM) Mortality Parkinson disease (PD)

Contacts and locations

Locations

  • Department of Public Health, Section of Epidemiology

    Copenhagen, Denmark

  • Human Nutrition Unit - Alimentació, Nutrició, Desenvolupament i Salut Mental (ANUT-DSM).

    Reus, Catalonia, 43201, Spain

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Other studies related to the condition(s) this trial covers.