Parkinson disease (disorder)

This early-stage trial is testing whether a single same-day treatment using a patient's own bone marrow cells is safe and tolerable for people with Parkinson's disease or related conditions. The procedure involves drawing bone marrow from the hip, giving one portion through an IV…

This study compares a new ultra-high resolution PET/CT scanner, the NeuroEXPLORER, with standard clinical PET/CT scanners for imaging the head and neck. Researchers aim to see if the new device provides more detailed images to improve diagnosis of conditions like dementia, Parkin…

This study tests whether a drug called crisugabalin can safely reduce pain in people with Parkinson's disease who have a type of pain called nociplastic pain. About 166 adults will take either the drug or a placebo twice a day for 12 weeks. Researchers will measure pain levels an…

This study tests whether a gentle electrical current applied to the back of the head (cerebellar tDCS) can improve both movement and mood in people with mild to moderate Parkinson's disease. Twenty-five participants will use a portable device at home for 8 days. Researchers will …

This study looks at whether a gentle electrical stimulation to the ear (auricular vagus nerve stimulation) combined with standard physical therapy can improve balance, walking, and other symptoms in people with Parkinson's disease. About 20 adults with mild to moderate Parkinson'…

This study looks at balance and movement problems in people with stroke, Parkinson's disease, or multiple sclerosis. Researchers will use special devices to measure how well participants can keep their balance and walk. The goal is to learn more about these issues so that rehabil…

This study looks at how tiredness affects daily life and muscle function in older adults (65+) and people with Parkinson's disease. Researchers will use questionnaires and simple exercises like handgrip and leg movements to measure fatigue. The goal is to better understand fatigu…