OVERACTIVE BLADDER

This study is testing a small device called eCoin that is implanted under the skin to stimulate a nerve in the leg. The goal is to help people who have sudden, strong urges to urinate and leak urine. About 200 adults with this condition will be followed for up to 2 years to see i…

This study looks at whether adding high-dose vitamin D to standard care (medication and behavior therapy) helps children with overactive bladder who have wetting accidents. About 180 children aged 5 and older with low vitamin D levels will take part. The goal is to see if this co…

This study tests a device that uses mild electrical pulses to calm bladder nerves in men with overactive bladder. About 150 men will use the device for up to a year. The goal is to reduce urgent bathroom trips and improve daily life.

This study tests a new ultrasound technique called Quantitative Ultrasound Bladder Vibrometry to check for abnormal bladder function without using catheters or needles. Researchers at Mayo Clinic will compare the new method to standard tests in adults with overactive bladder or e…

This study looks at a new way to use X-rays during a procedure for overactive bladder. The goal is to see if a different X-ray setting can reduce radiation exposure while still placing the device correctly. About 44 adults with overactive bladder will take part. The study compare…

This study tests whether a daily 500 mg cranberry extract (NDS-446) can change the natural bacteria in the bladder to reduce frequent and urgent bathroom trips in women who do not have leakage. Researchers will compare bacteria samples and symptom scores before and after 12 weeks…

This study is testing a new device called Tensi+ that uses mild electrical pulses to help people with overactive bladder. Researchers will track 500 adults for one year to see if their symptoms improve and if the device is safe. The goal is to understand who benefits most from th…

This study tests a noninvasive brain stimulation technique called rTMS to improve overactive bladder symptoms in women with multiple sclerosis. About 29 women will receive either real or sham treatment over 10 sessions. The goal is to see if targeting specific brain areas can red…

This study tests whether a small, at-home nerve stimulation device can help women in rural areas manage overactive bladder symptoms. About 38 women will use the device themselves and track their symptoms. The goal is to see if this approach is practical and improves quality of li…

This study tests whether adding Botox injections into the bladder during standard prostate surgery (HoLEP) can better relieve overactive bladder symptoms like sudden urges and frequent urination. About 80 men aged 18-89 with these symptoms will be randomly assigned to get either …

This study aims to collect electrical signals from the body in people with overactive bladder, fecal incontinence, or urinary retention. About 300 adults who are already scheduled for a Medtronic InterStim implant will have their signals recorded at several points during their th…

This study aims to understand how electrical stimulation of a nerve in the lower back helps people with overactive bladder. Researchers will measure signals from the nerve during stimulation to see which settings work best. The study involves 15 adults who are already scheduled t…