OVERACTIVE BLADDER

This study tests whether mirabegron, a drug used for overactive bladder, can help people with dry age-related macular degeneration (AMD). Researchers will give 312 patients aged 50-80 either mirabegron or a standard bladder drug for 12 months and check for changes in the retina. …

This study looks at whether three proteins found in urine—RhoA, NGF, and BDNF—can help doctors diagnose and track overactive bladder in children aged 4 to 18 who also have low vitamin D. Researchers will measure these proteins using a lab test and compare them to symptom scores. …

This study tests two treatments—mirabegron (a drug) and exercise-based behavioral therapy—for overactive bladder in people with Parkinson's disease. Researchers want to see if combining treatments helps those who don't respond to one alone. The trial will involve 146 participants…

This study tests whether a mix of nitrous oxide (laughing gas) and oxygen can reduce pain during in-office bladder Botox injections for overactive bladder. About 96 adult women will receive either the gas plus standard numbing medicine or a sham mask plus standard care. Participa…

This study looks at whether giving patients a standing prescription for an antibiotic (Macrobid) to use at the first sign of a urinary tract infection after Botox treatment for overactive bladder can reduce the need for phone calls, clinic visits, or emergency room trips. About 2…

This study tests whether adding gabapentin to the standard drug solifenacin works better than solifenacin alone for women with overactive bladder. Sixty women will be randomly assigned to one of the two treatments and followed for 3 months. The goal is to see if the combination i…

This study tests whether taking probiotics twice a day for 12 weeks can reduce how often people with overactive bladder (OAB) and anxiety need to urinate, and whether it can also lower their anxiety. All participants will also learn bladder training techniques. The study will com…

Researchers are adapting the Urgency, Severity, and Impact Questionnaire (USIQ) for Turkish-speaking women with overactive bladder. The study will enroll 130 women to test how well the translated questionnaire measures urgency symptoms and their effect on daily life. Participants…

This study will follow 500 Beijing residents aged 60 and older to see how urinary function (like bladder and kidney health) relates to the development of multiple chronic conditions such as diabetes, heart disease, and Alzheimer's. Participants will have regular health checks, bl…

This study will test a mobile app version of a bladder diary in 40 Portuguese adults with overactive bladder or urinary incontinence. Participants will use the app for one month and then answer questions about how easy it was to use and whether they prefer it over paper diaries. …

This study looks at whether people with overactive bladder can be monitored at home after receiving botulinum toxin injections, instead of going to the hospital. About 112 participants will be randomly assigned to either home or hospital follow-up. The goal is to see if home moni…

This study looks at how two different weight loss methods—medication (GLP-1 drugs) and surgery—change pelvic floor symptoms like bladder control, urgency, and vaginal prolapse in women. About 200 women aged 18-89 with a BMI of 30 or higher will be followed. The goal is to help do…