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Could a bladder pill save your sight? new trial tests mirabegron for dry AMD

NCT ID NCT07305298

First seen Jan 07, 2026 · Last updated Jun 23, 2026 · Updated 30 times

Summary

This study tests whether mirabegron, a drug used for overactive bladder, can help people with dry age-related macular degeneration (AMD). Researchers will give 312 patients aged 50-80 either mirabegron or a standard bladder drug for 12 months and check for changes in the retina. The goal is to see if mirabegron can slow or improve the eye condition.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Federico II

    Naples, Italy

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Mirabegron (50 mg daily)

What this could lead to

If it works, this could point toward a new treatment for dry AMD using an existing drug.

What could go wrong

This is a small, early-stage trial with no random assignment, so results may not be conclusive. The drug is not designed for eye disease and may not improve vision.

Conditions

The condition(s) this trial relates to.

overactive bladder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.