Could a bladder pill save your sight? new trial tests mirabegron for dry AMD

NCT ID NCT07305298

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tests whether mirabegron, a drug used for overactive bladder, can help people with dry age-related macular degeneration (AMD). Researchers will give 312 patients aged 50-80 either mirabegron or a standard bladder drug for 12 months and check for changes in the retina. The goal is to see if mirabegron can slow or improve the eye condition.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
Mirabegron (50 mg daily)
What this could lead to
If it works, this could point toward a new treatment for dry AMD using an existing drug.
What could go wrong
This is a small, early-stage trial with no random assignment, so results may not be conclusive. The drug is not designed for eye disease and may not improve vision.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Federico II

    Naples, Italy

More trials for these conditions

Other studies related to the condition(s) this trial covers.