Vitamin d boosts bladder control in kids? new trial investigates.
NCT ID NCT06201013
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether adding high-dose vitamin D to standard care helps children with overactive bladder (wet) reach their goal of zero leakage. About 180 children aged 5 and older with low vitamin D levels will receive either standard treatment alone or standard treatment plus daily vitamin D for 12 weeks. Researchers will track symptoms, nerve repair markers, and family costs to see if the combination works better.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 180 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Apr 2026
An estimate. Start dates often move.
- Expected to finish
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Apr 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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5 to 18 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Children older than or equal to 5 years of age with a diagnosis of wet OAB (the diagnosis followed the latest guidelines of ICCS) attending the outpatient clinic of the Department of Urology of the Affiliated Children's Hospital of Chongqing Medical University, * children with serum vitamin D levels below 35 ng/ml as indicated by the tests conducted by the hospital * children whose guardians have given their informed consent, are able to ensure compliance and have signed a paper-based informed consent form. Exclusion Criteria: * Those with urinary malformations or serious diseases (e.g., hypospadias, cryptorchidism, posterior urethral valvulae, vesicoureteral reflux, neurogenic bladder, urinary tumors, urinary stones, bladder and urethral injuries, etc.) * Those with neurological disorders (e.g., epilepsy, spinal cord injuries, spinal dysplasia, spinal embolism syndrome, multiple sclerosis, and autism spectrum disorders, etc.) * People with serious heart disease, abnormal liver and kidney function, lung disease, bone deformity, serious digestive tract disease, genetic metabolic disease * People with history of gastrointestinal surgery and urological surgery * People with dry stools and long-term constipation * People who are taking anticonvulsant and antiepileptic drugs, hormones, and anti-tuberculosis drugs * People with history of hypercalcemia, hyperphosphatemia with renal rickets * People who have had unexplained hematuria and hematuria with renal rickets within the last year * People who have been suffering from severe heart disease or chronic diabetes. * participation in other clinical studies at the time of consultation or during the follow-up period of other clinical studies * unwillingness to participate in this study
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Children's Hospital of Chongqing Medical University
RECRUITINGChongqing, Chongqing Municipality, 400000, China
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Other studies related to the condition(s) this trial covers.
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