OSTEOPENIA

This study looks at whether a weekly low-dose rapamycin pill (everolimus), resistance training (like lifting weights), or both can improve bone formation and muscle function in women aged 60-75 who have lower bone density but not osteoporosis. About 148 women will be randomly ass…

This study looks at whether whole-body vibration therapy can help women with low bone density recover better after total knee replacement. 48 women will be split into three groups: vibration only, vibration plus exercise, or standard rehab. Researchers will measure bone turnover,…

This study tests whether a single dose of zoledronic acid can prevent the bone loss that often happens when people start HIV medication. About 110 adults newly diagnosed with HIV will either receive the drug or just be monitored. Researchers will track bone density over four year…

This study tests whether veverimer, a drug that lowers acid levels in the body, can reduce bone breakdown in adults aged 50 and older with osteopenia (low bone density). Sixty participants will take either veverimer or a placebo daily or every other day for 8 weeks. Researchers w…

This study looks at whether a new ultrasound technology called REMS can safely measure bone density in children aged 5 to 18 who have conditions that weaken bones, like osteoporosis or growth hormone deficiency. Unlike the current standard (DXA), REMS uses no radiation. The goal …

This study is testing a new portable ultrasound device that measures bone density in the lower leg without using radiation. Researchers will compare its results to the standard X-ray method (DXA) in 350 healthy adults aged 21 to 55. The goal is to see if the ultrasound device can…

This study aims to make sure lab tests, equipment, and procedures used in research on obesity, diabetes, heart disease, and bone disorders are accurate and give consistent results. It will involve up to 100 healthy volunteers and people with these conditions, aged 18 to 100. The …