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Weekly rapamycin and exercise may boost bone health in older women

NCT ID NCT07191353

First seen Nov 01, 2025 · Last updated May 23, 2026 · Updated 30 times

Summary

This study looks at whether a weekly low-dose rapamycin pill (everolimus), resistance training (like lifting weights), or both can improve bone formation and muscle function in women aged 60-75 who have lower bone density but not osteoporosis. About 148 women will be randomly assigned to one of four groups: pill only, placebo only, pill plus exercise, or placebo plus exercise. The main goal is to see changes in a bone formation marker after 24 weeks.

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Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Department of Endocrinology, Odense University Hospital

    RECRUITING

    Odense, Region Syddanmark, 5000, Denmark

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Institute of Sports Medicine, Bispebjerg Hospital

    RECRUITING

    Bispebjerg, Region Sjælland, 2200, Denmark

    Contact Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

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