OSTEOARTHRITIS (OA) OF THE KNEE
Clinical trials for OSTEOARTHRITIS (OA) OF THE KNEE explained in plain language.
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New daily pill aims to halt knee cartilage loss
Disease control Not yet recruitingThis early-stage study is testing whether a daily oral medication called Mobithron Advance can slow down or even reverse cartilage loss in people with knee osteoarthritis. Researchers will follow 84 adults over 50 for one year, using MRI scans to measure cartilage thickness and q…
Matched conditions: OSTEOARTHRITIS (OA) OF THE KNEE
Phase: EARLY_PHASE1 • Sponsor: Universiti Sains Malaysia • Aim: Disease control
Last updated Apr 03, 2026 14:42 UTC
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Weight loss shot before knee surgery: could it cut complications?
Disease control Not yet recruitingThis study is testing if using a weight loss medication (semaglutide) before total knee replacement surgery can lead to better outcomes for patients who are obese. It will involve 54 people with knee arthritis who are scheduled for surgery. The main goal is to see if this approac…
Matched conditions: OSTEOARTHRITIS (OA) OF THE KNEE
Phase: EARLY_PHASE1 • Sponsor: The University of Hong Kong • Aim: Disease control
Last updated Mar 30, 2026 14:34 UTC
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Could a smaller needle or a quick spray make your knee injection hurt less?
Symptom relief Not yet recruitingThis study aims to find ways to make steroid injections for knee osteoarthritis less painful. Researchers will test if using a smaller needle or a numbing spray called ethyl chloride reduces pain during and after the injection. They will also see if having less pain from the inje…
Matched conditions: OSTEOARTHRITIS (OA) OF THE KNEE
Phase: PHASE4 • Sponsor: University of California, Davis • Aim: Symptom relief
Last updated Apr 04, 2026 02:20 UTC
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Fat-Fueled diet tested to fight pain and brain fog
Symptom relief Not yet recruitingThis study is testing if a supervised ketogenic diet (a very low-carb, high-fat eating plan) can help reduce pain and improve thinking in older adults who have both osteoarthritis and mild memory problems. Ten participants will follow the diet, and researchers will check their pa…
Matched conditions: OSTEOARTHRITIS (OA) OF THE KNEE
Phase: NA • Sponsor: University of Kansas Medical Center • Aim: Symptom relief
Last updated Apr 02, 2026 14:56 UTC
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New injection aims to cut opioid use after knee surgery
Symptom relief Not yet recruitingThis study is looking at a long-acting pain injection (Zynrelef) given during robotic knee replacement surgery. The goal is to see if it helps patients have less pain and need fewer opioid painkillers in the first three days after surgery compared to standard pain injections. Res…
Matched conditions: OSTEOARTHRITIS (OA) OF THE KNEE
Phase: PHASE4 • Sponsor: Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute) • Aim: Symptom relief
Last updated Mar 31, 2026 12:12 UTC
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New pill aims to beat opioids for surgery pain
Symptom relief Not yet recruitingThis study is testing if a new oral medication called suzetrigine works as well as or better than the standard opioid oxycodone for pain after knee replacement surgery. Researchers want to see if suzetrigine can control pain effectively while reducing the total amount of opioid m…
Matched conditions: OSTEOARTHRITIS (OA) OF THE KNEE
Phase: PHASE4 • Sponsor: University of Louisville • Aim: Symptom relief
Last updated Mar 23, 2026 15:16 UTC