OSTEO ARTHRITIS KNEE

This early-phase study tested whether a single injection of donor bone-marrow stem cells (StromaForte) is safe for people with mild-to-moderate knee osteoarthritis. Twelve adults received the injection and were monitored for side effects over 24 weeks. The main goal was safety, n…

This phase 3 study tested a weekly injection called retatrutide in 445 people who are overweight or have obesity and also have knee osteoarthritis. The goal was to see if it reduces knee pain and helps with weight loss. Participants received either the drug or a placebo for about…

This study tested whether supervised exercise, a diclofenac gel, or both together work better for knee osteoarthritis pain and function. 79 adults aged 40-65 with mild to moderate knee OA took part. The goal was to see which approach offers the most relief for this common, painfu…

This study tested whether using a cold and compression brace for six weeks after knee replacement surgery helps reduce pain and the need for painkillers. 208 adults who had a total or partial knee replacement took part. They used the brace five times a day for 20 minutes and were…

This study looked at whether adding a gentle joint-mobilization technique (Mulligan's) to basic isometric exercises helps people with knee osteoarthritis. 50 adults aged 40-65 with moderate knee arthritis took part. Researchers measured pain, movement, and daily function to see i…

This study tested whether a device called the OrthoCor Advanced System can reduce pain and improve quality of life in people with knee osteoarthritis. Twenty-three adults with knee pain for at least 3 months used the device for 30 minutes twice daily over 4 weeks. The device deli…

This early study tested whether injecting a special mixture of cells from a person's own belly fat into their arthritic knee is safe and doable. Nine adults with knee osteoarthritis received the injection. The main goal was to check for side effects, not to measure pain relief, s…

This study tested a new drug called LEVI-04 to see if it can reduce pain in people with knee osteoarthritis. About 518 adults with knee pain took either the drug or a placebo. The goal was to measure pain changes using a standard knee pain scale. This is not a cure, but aims to e…

This study compared a single injection of sterile amniotic fluid to the standard steroid shot for knee osteoarthritis. 60 adults with moderate knee arthritis who had not gotten relief from other treatments took part. The main goal was to see if the amniotic fluid could reduce the…

This study looked at whether adding deep breathing or simple yoga poses to standard physical therapy could help people with knee osteoarthritis feel less afraid of moving. 40 adults aged 40-60 with severe knee pain took part. The results showed that both approaches helped reduce …

This study tested a movement therapy called Mulligan mobilization in 36 people with knee osteoarthritis. The goal was to see if it could reduce pain and improve how muscles work. Participants were aged 50 to 70 with moderate knee pain. The therapy involves gentle, repeated moveme…

This study tested a two-week home treatment combining gentle brain stimulation (tDCS) with mindfulness meditation in 208 older adults with knee osteoarthritis. The goal was to see if this drug-free approach could reduce pain and improve daily function. Results focused on changes …

This study looked at whether doing two things at once (dual task) changes how muscle strength and performance are measured in people with knee osteoarthritis. Researchers tested 60 adults aged 40-65 with mild to moderate knee osteoarthritis. They measured leg strength, sit-to-sta…

This study tested a personalized web-based care plan for over 5,700 adults with knee or hip osteoarthritis. The goal was to help patients and their doctors make more informed decisions about treatments, including whether to have joint replacement surgery. The study measured how w…