Normal pressure hydrocephalus

This lab study uses leftover spinal fluid from 10 patients with normal pressure hydrocephalus to see if common numbing medicines form crystals. Researchers mix different drugs and watch for crystals over 60 minutes. The goal is to understand risks, not to treat patients directly.

This study explores whether a special type of MRI called flow MRI can improve the diagnosis and management of normal pressure hydrocephalus, a condition where excess fluid builds up in the brain's cavities. Researchers will measure how cerebrospinal fluid and blood move through t…

This study looked at 75 older adults with suspected normal pressure hydrocephalus, a condition that can cause a reversible form of dementia. Researchers used a combination of fluid infusion tests and special MRI scans to better understand how brain fluid and pressure interact. Th…

This completed observational study looked at 29 people with suspected normal pressure hydrocephalus (NPH), a condition where fluid builds up in the brain. Researchers used a special MRI technique called DTI-ALPS to measure the function of the brain's waste-clearing 'glymphatic sy…

This study looked at proteins in the spinal fluid of 100 people with symptoms of normal pressure hydrocephalus, such as trouble walking, memory loss, and bladder control issues. Researchers used a new method to analyze the fluid and compared results with walking tests and brain s…

This study tested whether a special MRI scan (flow MRI) can predict how well patients with normal pressure hydrocephalus will respond to surgery. Currently, doctors use a lumbar puncture (spinal tap) to make this prediction. The study enrolled 30 adults and measured cerebrospinal…