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MRI may replace spinal tap for predicting surgery success

NCT ID NCT01815775

Knowledge-focused Sponsor: Centre Hospitalier Universitaire, Amiens Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tested whether a special MRI scan (flow MRI) can predict how well patients with normal pressure hydrocephalus will respond to surgery. Currently, doctors use a lumbar puncture (spinal tap) to make this prediction. The study enrolled 30 adults and measured cerebrospinal fluid flow using MRI. If successful, this could provide a non-invasive alternative to lumbar puncture.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If flow MRI proves as effective as lumbar puncture, it could offer a non-invasive way to predict who will benefit from surgery.
What could go wrong
This is a small, early-phase study with only 30 participants. The results may not be conclusive or apply to all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Early phase 1

The earliest testing in people: a first look at safety, in a very small group.

Participants

30 people

The number who actually took part.

Start date

Mar 2006

Finished

Jul 2009

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

20 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * age: over 20 years * diagnostic of normal pressure hydrocephalus * ventricular dilation visible on radiological examination * patients gave their written informed consent Exclusion Criteria: * age: less than 20 years * MRI contra-indication * pregnancy * lumbar puncture within 48 hours before MRI * cardiac arrhythmia * cerebral/lacunar stroke

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Conditions

The condition(s) this trial relates to.

dementia normal pressure hydrocephalus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Normal pressure hydrocephalus

Contacts and locations

Locations

  • CHU Amiens

    Amiens, Picardie, 80054, France

More trials for these conditions

Other studies related to the condition(s) this trial covers.