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Can a Flow-Sensitive MRI unlock the secrets of a treatable brain condition?

NCT ID NCT01909960

Knowledge-focused Sponsor: Centre Hospitalier Universitaire, Amiens Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study explores whether a special type of MRI called flow MRI can improve the diagnosis and management of normal pressure hydrocephalus, a condition where excess fluid builds up in the brain's cavities. Researchers will measure how cerebrospinal fluid and blood move through the brain in 144 adults with symptoms like walking trouble and memory loss. The goal is to see if these flow measurements can help doctors better decide who might benefit from treatment.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Flow MRI (phase-contrast magnetic resonance imaging)
What this could lead to
If flow MRI proves useful, it could become a standard tool to diagnose normal pressure hydrocephalus more accurately and guide treatment decisions.
What could go wrong
This is an observational study, not a treatment trial. It will not directly improve symptoms, and the added value of flow MRI over standard imaging is still uncertain.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

144 people

The number who actually took part.

Started

May 2012

Finished

Aug 2020

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Ventricular dilation seen on morphological magnetic resonance imaging (MRI) * Walking disorder * Cognitive disorder * Participants gave their written informed consent Exclusion Criteria: * Contra-indication to MRI * Obstructive tumoral hydrocephalus * Curatorship or tutorship * Pregnancy or lactation * No social assurance

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Conditions

The condition(s) this trial relates to.

dementia normal pressure hydrocephalus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Normal pressure hydrocephalus

Contacts and locations

Locations

  • CHU Amiens

    Amiens, Picardie, 80054, France

  • CHU Lille

    Lille, Hauts-de-France, 59000, France

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