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New MRI method could spot reversible dementia more accurately

NCT ID NCT05068128

Knowledge-focused Sponsor: Centre Hospitalier Universitaire, Amiens Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at 75 older adults with suspected normal pressure hydrocephalus, a condition that can cause a reversible form of dementia. Researchers used a combination of fluid infusion tests and special MRI scans to better understand how brain fluid and pressure interact. The goal was to create a new way to identify which patients would benefit from a shunt to drain excess fluid, improving diagnosis beyond current methods.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

75 people

The number who actually took part.

Started

Jan 2022

Finished

Sep 2024

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Patients with suspected active hydrocephalus (HA) known as "normal pressure" and with Flow MRI and CSF infusion test.

Ages

55 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * age \> 55 years * Patients with suspected active hydrocephalus (HA) known as "normal pressure": * Ventricular dilatation: Evans index \> 0.3 * Patients with cognitive impairment, and/or gait disorders and/or urinary incontinence or a combination of these three symptoms. * Absence of other neurological diseases that could cause ventriculomegaly. * Information and collection of the patient's non opposition Exclusion Criteria: * All patients with neurological disease other than active hydrocephalus will be excluded. * Individuals who cannot tolerate an MRI examination * All individuals with implants, pacemakers, prostheses and ferromagnetic objects * Patients under guardianship, curators or safeguard of justice

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Conditions

The condition(s) this trial relates to.

dementia hydrocephalus intracranial hypertension normal pressure hydrocephalus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Cerebral blood flows Dementia Hydrocephalus Infusion test Intracranial pressure Phase contrast mri

Contacts and locations

Locations

  • CHU Amiens

    Salouël, 80480, France

More trials for these conditions

Other studies related to the condition(s) this trial covers.