Normal pressure hydrocephalus

Researchers are studying whether phase-contrast MRI can measure cerebrospinal fluid flow well enough to improve diagnosis and prognosis in people with normal pressure hydrocephalus. The trial enrolls adults who have gait problems plus memory issues or urinary symptoms, along with…

This study tests a new MRI technique to measure how cerebrospinal fluid flows in the brain. Researchers will compare 50 healthy volunteers and patients with conditions like Alzheimer's disease or normal pressure hydrocephalus. The goal is to improve diagnosis and understanding of…

This study looks at why some cancer patients develop neurological problems after receiving immunotherapy drugs called checkpoint inhibitors. Researchers will analyze spinal fluid and blood from 160 participants to find immune cells that may mistakenly attack the nervous system. T…

This study follows 140 people with early signs of normal pressure hydrocephalus (NPH) to see if brain scans and fluid tests can predict who will get worse and need shunt surgery. Participants include those with mild symptoms, those with clear NPH, and healthy volunteers. The goal…

This study looks at how sleep apnea changes pressure in the brain and belly during sleep in people with normal-pressure hydrocephalus. Researchers want to see if these pressure changes affect how well a surgically placed shunt (a tube that drains fluid from the brain) works. The …

This study is gathering information from 4500 people who have or will have brain surgery for conditions like aneurysms, tumors, epilepsy, and Parkinson's disease. The goal is to find patterns that help doctors predict how well someone will recover. By standardizing how outcomes a…

This study looks at 100 older adults with normal pressure hydrocephalus (NPH) to find out why some get better after a shunt surgery and others do not. Researchers will use brain scans, blood tests, and wearable monitors to check for nerve damage and signs of dementia. The goal is…