MYELOPROLIFERATIVE NEOPLASM
Clinical trials for MYELOPROLIFERATIVE NEOPLASM explained in plain language.
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New drug combo tested for aggressive blood cancers
Disease control CompletedThis study tested a combination of two drugs, ruxolitinib and CPX-351, for people with advanced forms of certain blood cancers. The main goals were to find the safest dose of the combination and to see how well it worked to control the disease. The treatment aimed to reduce cance…
Matched conditions: MYELOPROLIFERATIVE NEOPLASM
Phase: PHASE1, PHASE2 • Sponsor: Ohio State University Comprehensive Cancer Center • Aim: Disease control
Last updated Apr 03, 2026 14:41 UTC
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New hope for blood cancer patients: experimental combo aims to stop transplant complications
Disease control CompletedThis study tested a new three-drug combination (PTCy, sirolimus, and VIC-1911) to prevent two major problems after a stem cell transplant: graft-versus-host disease (GVHD) and cancer relapse. It involved 16 adults with blood cancers like leukemia and lymphoma who received a high-…
Matched conditions: MYELOPROLIFERATIVE NEOPLASM
Phase: PHASE1, PHASE2 • Sponsor: Masonic Cancer Center, University of Minnesota • Aim: Disease control
Last updated Mar 30, 2026 14:34 UTC
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New hope for blood cancer patients: gentler transplants from family donors
Disease control CompletedThis study tested a less intense bone marrow transplant procedure for adults with various blood cancers who needed a transplant but did not have a fully matched donor. It used stem cells from a half-matched family member (like a parent, child, or sibling) after a milder pre-trans…
Matched conditions: MYELOPROLIFERATIVE NEOPLASM
Phase: PHASE2 • Sponsor: H. Lee Moffitt Cancer Center and Research Institute • Aim: Disease control
Last updated Mar 20, 2026 14:48 UTC
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Study probes deadly double threat: blood cancers and COVID-19
Knowledge-focused CompletedThis study aimed to understand how COVID-19 affects people with rare blood cancers called Myeloproliferative Neoplasms (MPNs). Researchers followed 552 patients with both MPN and COVID-19 to see what factors led to worse outcomes, like blood clots or death. The goal was to gather…
Matched conditions: MYELOPROLIFERATIVE NEOPLASM
Sponsor: FROM- Fondazione per la Ricerca Ospedale di Bergamo- ETS • Aim: Knowledge-focused
Last updated Mar 02, 2026 15:21 UTC